Emergence of ancient convalescent plasma (CP) therapy: To manage COVID-19 pandemic

被引:3
作者
Dassarma, Barsha [1 ]
Tripathy, Satyajit [1 ]
Matsabisa, Motlalepula [1 ]
机构
[1] Univ Free State, Fac Hlth Sci, Sch Med, Dept Pharmacol, ZA-9300 Bloemfontein, South Africa
关键词
Convalescent plasma (CP) therapy; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Passive immune therapy; Antibody-dependent enhancement (ADE); EBOLA-VIRUS DISEASE; INFLUENZA; INFECTION; BLOOD; SERUM;
D O I
10.1016/j.tracli.2020.11.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Since December 2019, the human populations of the 195 global countries continue experiencing grave health and life threats due to the current COVID-19 pandemic. As a result of the novelty of the pathogen, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), at present there is lack of preventive as well as therapeutic options for treating and managing the infection. The use of ancient immunotherapeutic technique - the convalescent plasma (CP) therapy, may act as an immediate and available option to control the COVID-19 pandemic. This review provides a concept and understanding on the CP therapy, its potential to control SARS-CoV-2 pandemic. The CP therapy might act as an immediate saviour for society from the virus. Although the CP therapy has exert affirmative result against COVID-19 it has not been recommended for long time use in COVID-19 and this review gives support for its possible application. (C) 2020 Published by Elsevier Masson SAS on behalf of Societe francaise de transfusion sanguine (SFTS).
引用
收藏
页码:123 / 127
页数:5
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