Synthesis of 3,3-disubstituted oxindoles

被引:26
|
作者
Liu, Kevin G. [1 ]
Robichaud, Albert J. [1 ]
机构
[1] Wyeth Res, Chem & Screeing Sci, Princeton, NJ 08543 USA
关键词
D O I
10.1016/j.tetlet.2006.11.041
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel and efficient two-step synthetic sequence for the preparation of 3,3-disubstituted oxindoles was developed starting from arylhydrazines and alpha-branched aldehydes via Fischer indole type synthesis followed by imine oxidation. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码:461 / 463
页数:3
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