Highly enantiofacial protonation of prochiral lithium enolates with chiral beta-hydroxy sulfoxides

被引：37

作者：

Kosugi, H

Hoshino, K

Uda, H

机构：

[1] Inst. for Chemical Reaction Science, Tohoku University, Sendai 980-77, Katahira, Aoba-ku

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 39期

关键词：

D O I：

10.1016/S0040-4039(97)01618-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Highly enantioselective protonation of prochiral lithium enolates is disclosed. The present method employed (S,R-S)-CF3-hydroxy sulfoxide (3b) as the chiral protonating agent, and the protonation of lithium enolates of cyclohexanone derivatives with 3b proceeded with high enantioselectivities. (C) 1997 Elsevier Science Ltd.

引用

页码：6861 / 6864

页数：4

共 31 条

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