The O-polysaccharide of Escherichia coli F5, which is structurally related to that of E. coli O28ab, provides cells only weak protection against bacteriophage attack

被引：6

作者：

Golomidova, A. K. ^{[1
]}

Naumenko, O. I. ^{[2
]}

Senchenkova, S. N. ^{[2
]}

Knirel, Y. A. ^{[1
,2
]}

Letarov, A. V. ^{[1
,3
]}

机构：

[1] Russian Acad Sci, SN Winogradsky Inst Microbiol, Fed Res Ctr, Fundamentals Biotechnol, Moscow 117312, Russia

[2] Russian Acad Sci, ND Zelinsky Inst Organ Chem, Moscow 119991, Russia

[3] Lomonosov Moscow State Univ, Fac Biol, Moscow 119991, Russia

来源：

ARCHIVES OF VIROLOGY | 2019年 / 164卷 / 11期

基金：

俄罗斯科学基金会;

关键词：

ANTIGEN; BARRIER;

D O I：

10.1007/s00705-019-04371-1

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Several types of Escherichia coli O-antigens form highly effective shields protecting the bacterial cell surface and preventing bacteriophages from interacting directly with their secondary (terminal) receptors. However, it is not clear if O-antigens of various types (O-serotypes) differ in their anti-phage protection efficacy. Here, we describe a new E. coli strain, F5, which has an E. coli O28ab-related O-antigen. Although the amount of O-antigen produced by this strain is comparable to that produced by other E. coli strains we tested, it appears to give the cells significantly lower protection against phage attack than other O-antigen types, such as the O-polysaccharide of E. coli F17, which we studied earlier.

引用

页码：2783 / 2787

页数：5