Highly efficient one-pot synthesis of 2-arylmethyl N-substituted anilines via Yb(OTf)3 catalyzed three-component reaction

被引：2

作者：

Wang Li-Min ^{[1
]}

Zhang Liang

Hu Liang

Tian He

机构：

[1] E China Univ Sci & Technol, Adv Mat Lab, Shanghai 200237, Peoples R China

[2] E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2007年 / 25卷 / 03期

关键词：

Yb(OTf)(3); 2-arylmethyl N-substituted aniline; aldehyde; 1-cyclohexen-2-one; amine;

D O I：

10.1002/cjoc.200790071

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient method has been developed for one-pot three-component coupling reactions of various aldehydes, 1-cyclohexen-2-one, and primary or secondary amines in the presence of a catalytic amount of Yb(OTf)(3) under mild conditions to afford the corresponding 2-arylmethyl N-substituted anilines in good yields. In addition, the catalyst was easily recovered and could be reused for at least four cycles without any loss of activity.

引用

页码：370 / 374

页数：5

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