Highly efficient one-pot synthesis of 2-arylmethyl N-substituted anilines via Yb(OTf)3 catalyzed three-component reaction

被引：2
作者：
Wang Li-Min [1 ]
Zhang Liang
Hu Liang
Tian He
机构：
[1] E China Univ Sci & Technol, Adv Mat Lab, Shanghai 200237, Peoples R China
[2] E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2007年 / 25卷 / 03期
关键词：
Yb(OTf)(3); 2-arylmethyl N-substituted aniline; aldehyde; 1-cyclohexen-2-one; amine;
D O I：
10.1002/cjoc.200790071
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient method has been developed for one-pot three-component coupling reactions of various aldehydes, 1-cyclohexen-2-one, and primary or secondary amines in the presence of a catalytic amount of Yb(OTf)(3) under mild conditions to afford the corresponding 2-arylmethyl N-substituted anilines in good yields. In addition, the catalyst was easily recovered and could be reused for at least four cycles without any loss of activity.
引用
收藏
页码：370 / 374
页数：5
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