Diabetes, kidney disease and anaemia: time to tackle a troublesome triad?

被引:17
作者
Al-Khoury, S.
Afzali, B.
Shah, N.
Thomas, S.
Gusbeth-Tatomir, P.
Goldsmith, D.
Covic, A.
机构
[1] C I Parhon Univ Hosp, Dialysis & Transplantat Ctr, Iasi 700503, Romania
[2] Guys Hosp, Dept Endocrinol & Diabet, London, England
[3] Guys Hosp, Dept Nephrol & Transplantat, London, England
基金
英国医学研究理事会;
关键词
D O I
10.1111/j.1742-1241.2006.01259.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Both chronic kidney disease (CKD) and type II diabetes mellitus (DM) are increasing in frequency among Western populations and both are potent risk factors for the development of anaemia. The presence of CKD and diabetes together represent the most important aetiopathogenic combination for the development of anaemia. New evidence has highlighted some of the underlying mechanisms which make diabetic patients more susceptible to dyserythropoiesis, particularly once they have developed concomitant CKD. In addition, recent publications from large-scale epidemiological studies have highlighted the impact of anaemia on diabetic patients. The purpose of this review was to focus on the pathophysiology and impact of anaemia in DM.
引用
收藏
页码:281 / 289
页数:9
相关论文
共 79 条
[1]   KIDNEY AND ERYTHROPOIESIS [J].
ADAMSON, JW ;
ESCHBACH, J ;
FINCH, CA .
AMERICAN JOURNAL OF MEDICINE, 1968, 44 (05) :725-+
[2]   SUPPRESSION OF RETINAL NEOVASCULARIZATION IN-VIVO BY INHIBITION OF VASCULAR ENDOTHELIAL GROWTH-FACTOR (VEGF) USING SOLUBLE VEGF-RECEPTOR CHIMERIC PROTEINS [J].
AIELLO, LP ;
PIERCE, EA ;
FOLEY, ED ;
TAKAGI, H ;
CHEN, H ;
RIDDLE, L ;
FERRARA, N ;
KING, GL ;
SMITH, LEH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (23) :10457-10461
[3]   Reduced kidney function and anemia as risk factors for mortality in patients with left ventricular dysfunction [J].
Al-Ahmad, A ;
Rand, WM ;
Manjunath, G ;
Konstam, MA ;
Salem, DN ;
Levey, AS ;
Sarnak, MJ .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2001, 38 (04) :955-962
[4]   Anaemia in diabetic patients with chronic kidney disease-prevalence and predictors [J].
Al-Khoury, S ;
Afzali, B ;
Shah, N ;
Covic, A ;
Thomas, S ;
Goldsmith, DJ .
DIABETOLOGIA, 2006, 49 (06) :1183-1189
[5]   Association of kidney function with anemia - The Third National Health and Nutrition Examination Survey (1988-1994) [J].
Astor, BC ;
Muntner, P ;
Levin, A ;
Eustace, JA ;
Coresh, J .
ARCHIVES OF INTERNAL MEDICINE, 2002, 162 (12) :1401-1408
[6]   PROGRESSIVE INCREASES IN LUMINAL GLUCOSE STIMULATE PROXIMAL SODIUM-ABSORPTION IN NORMAL AND DIABETIC RATS [J].
BANK, N ;
AYNEDJIAN, HS .
JOURNAL OF CLINICAL INVESTIGATION, 1990, 86 (01) :309-316
[7]   The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin [J].
Besarab, A ;
Bolton, WK ;
Browne, JK ;
Egrie, JC ;
Nissenson, AR ;
Okamoto, DM ;
Schwab, SJ ;
Goodkin, DA .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (09) :584-590
[8]   THE ANEMIA OF PRIMARY AUTONOMIC FAILURE AND ITS REVERSAL WITH RECOMBINANT ERYTHROPOIETIN [J].
BIAGGIONI, I ;
ROBERTSON, D ;
KRANTZ, S ;
JONES, M ;
HAILE, V .
ANNALS OF INTERNAL MEDICINE, 1994, 121 (03) :181-186
[9]   Anemia with erythropoietin deficiency occurs early in diabetic nephropathy [J].
Bosman, DR ;
Winkler, AS ;
Marsden, JT ;
Macdougall, IC ;
Watkins, PJ .
DIABETES CARE, 2001, 24 (03) :495-499
[10]   Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus -: A meta-analysis of controlled clinical trials [J].
Boulé, NG ;
Haddad, E ;
Kenny, GP ;
Wells, GA ;
Sigal, RJ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 286 (10) :1218-1227