A mathematical description of nerve fiber bundle trajectories and their variability in the human retina

被引：129

作者：

Jansonius, N. M. ^{[1
,2
]}

Nevalainen, J. ^{[3
]}

Selig, B. ^{[4
]}

Zangwill, L. M. ^{[5
]}

Sample, P. A. ^{[5
]}

Budde, W. M.

Jonas, J. B. ^{[6
]}

Lagreze, W. A. ^{[7
]}

Airaksinen, P. J. ^{[3
]}

Vonthein, R. ^{[8
]}

Levin, L. A. ^{[9
,10
]}

Paetzold, J. ^{[4
]}

Schiefer, U. ^{[4
]}

机构：

[1] Univ Groningen, Univ Med Ctr Groningen, Dept Ophthalmol, NL-9700 RB Groningen, Netherlands

[2] Erasmus MC, Dept Epidemiol & Biostat, Rotterdam, Netherlands

[3] Univ Eye Hosp Oulu, Oulu, Finland

[4] Univ Tubingen, Ctr Ophthalmol, D-72074 Tubingen, Germany

[5] Univ Calif San Diego, Hamilton Glaucoma Ctr, San Diego, CA 92103 USA

[6] Univ Eye Hosp Mannheim, Mannheim, Germany

[7] Univ Eye Hosp Freiburg, Freiburg, Germany

[8] Univ Tubingen, Dept Med Biometry, D-72074 Tubingen, Germany

[9] Univ Wisconsin, Dept Ophthalmol & Visual Sci, Madison, WI 53706 USA

[10] Univ Montreal, Dept Ophthalmol, Montreal, PQ H3C 3J7, Canada

来源：

VISION RESEARCH | 2009年 / 49卷 / 17期

关键词：

Glaucoma; Neuro-ophthalmology; Perimetry; Optic nerve head; OPTICAL COHERENCE TOMOGRAPHY; VISUAL-FIELD LOSS; LAYER THICKNESS; GLAUCOMA; HEAD; EYES; ELLIPSOMETRY; PHOTOGRAPHY;

D O I：

10.1016/j.visres.2009.04.029

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We developed a mathematical model wherein retinal nerve fiber trajectories can be described and the corresponding inter-subject variability analyzed. The model was based on traced nerve fiber bundle trajectories extracted from 55 fundus photographs of 55 human subjects. The model resembled the typical retinal nerve fiber layer course within 20 degrees eccentricity. Depending on the location of the visual field test point, the standard deviation of the calculated corresponding angular location at the optic nerve head circumference ranged from less than 1 degrees to 18 degrees, with an average of 8.8 degrees. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：2157 / 2163

页数：7

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