A facile three-component solid phase synthesis of steroidal A-ring fused pyrimidines under microwave irradiation

被引：25

作者：

Barthakur, Madan G. ^{[1
]}

Gogoi, Shyamalee ^{[1
]}

Dutta, Mandakini ^{[1
]}

Boruah, Romesh C. ^{[1
]}

机构：

[1] NE Inst Sci & Technol, Div Med Chem, Jorhat 785006, Assam, India

来源：

STEROIDS | 2009年 / 74卷 / 09期

关键词：

Heterosteroids; Arylaldehyde; Pyrimidine; Microwave; Ammonium acetate; ONE-POT SYNTHESIS; BIOLOGICAL EVALUATION; AZASTEROIDS; AGENTS;

D O I：

10.1016/j.steroids.2009.03.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The preparation of ring-A fused pyrimidines at the steroidal 2,3-position is herein described. The novel steroidal pyrimidines were prepared from the solid phase three-component reaction of 2-hydroxymethylene-3-keto steroids, arylaldehydes and ammonium acetate under microwave irradiation. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：730 / 734

页数：5

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