The influence of prostate volume on prostate cancer detection

Objectives: The influence of prostate volume on the positive yield of the systematic sector biopsy is logical and has been demonstrated in numerous reports. Methods: Literature on prostate biopsy was reviewed and a selection of articles made. Keywords used for the Medline search included: Prostate cancer, Biopsy, Diagnosis. Results: Sextant biopsies have the highest positive biopsy rate (less than or equal to40 g) in small prostates (<20 g), whereas in large prostate (80-90 cc) it drops to 10% only. Conclusions: The present paper reviews the influence of total and peripheral zone volumes of the prostate on prostate cancer detection rates. (C) 2002 Elsevier Science B.V. All rights reserved.