Dietary nitrate - Good or bad?

被引:105
作者
Gilchrist, Mark [1 ]
Winyard, Paul G. [1 ]
Benjamin, Nigel [1 ]
机构
[1] Univ Exeter, Peninsula Coll Med & Dent, Inst Biomed & Clin Sci, Exeter EX1 2LU, Devon, England
来源
NITRIC OXIDE-BIOLOGY AND CHEMISTRY | 2010年 / 22卷 / 02期
关键词
Dietary nitrate; Nitrate; Nitrite; Blood pressure; Endothelial function; Ischemia reperfusion injury; Platelet function; Host defence; Exercise performance; Nitrosamine; Methemoglobinemia; Nitrated lipid; Gastro-intestinal protection; NITRIC-OXIDE PATHWAY; MUCOSAL BLOOD-FLOW; L-ARGININE; ISCHEMIA/REPERFUSION INJURY; XANTHINE OXIDOREDUCTASE; INORGANIC NITRATE; ACIDIFIED NITRITE; FATTY-ACIDS; OLEIC ACID; IN-VIVO;
D O I
10.1016/j.niox.2009.10.005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
There has now been a great deal written about inorganic nitrate in both the popular press and in scientific journals. Papers in the 1970s warned us that inorganic nitrate could theoretically be metabolised in the human body to N-nitroso compounds, many of which are undoubtedly carcinogenic. More recently there is evidence that nitrate can undergo metabolic conversion to nitrite and nitric oxide and perform a useful protective function to prevent infection, protect our stomach, improve exercise performance and prevent vascular disease. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:104 / 109
页数:6
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