Prognostic value of B-type natriuretic peptide in unstable angina and non-ST-elevation myocardial infarction

被引：1

作者：

Jose Molina-Mora, Maria ^{[1
]}

Cabrera-Bueno, Fernando ^{[1
]}

Jimenez-Navarro, Manuel ^{[1
]}

Linde-Estrella, Antonio ^{[1
]}

Manuel Garcia-Pinilla, Jose ^{[1
]}

de Teresa-Galvan, Eduardo ^{[1
]}

机构：

[1] Hosp Univ Virgen Victoria, Serv Cardiol, Malaga, Spain

来源：

MEDICINA CLINICA | 2009年 / 133卷 / 15期

关键词：

B-type natriuretic peptide; Non-ST-segment elevation acute coronary syndromes; Prognosis; N-TERMINAL PROATRIAL; RISK STRATIFICATION; ASSOCIATION; MARKERS; GUIDELINES; ADMISSION; COMMITTEE; SOCIETY;

D O I：

10.1016/j.medcli.2009.04.057

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background and objective: The B-type natriuretic peptide (BNP) has recently emerged as a prognostic marker in acute coronary syndromes (ACS). This role is based on results from randomized trials and other high selected Population studies. The aim of this Study was to determine the prognostic value of BNP in unselected patients with non-ST-elevated-ACS. Patients and method: BNP plasma concentrations were measured in 100 consecutive patients admitted in 2007 with non-ST-elevated-ACS, taking as cut-off value 80 pg/ml (high BNP levels on 48% of patients). Results: After one year-of follow-up, 21 major adverse cardiovascular events occurred: 12 ACS, 7 hospitalizations for heart failure and 2 sudden cardiac deaths. No relationship was found between BNP levels and events on follow-up. BNP > 80 pg/ml was the only independent predictor of heart failure and death. No relationship was found between high levels of BNP and coronary events during the follow-up. Conclusions: BNP was an independent predictor of heart failure and mortality in unselected patients with non-ST-elevated-ACS. (C) 2009 Elsevier Espana, S.L. All rights reserved.

引用

页码：569 / 573

页数：5

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