Effects of lupane and oleanane β-enaminoketones on the number and morphology of white blood cells

被引：2

作者：

Anikina, L. V. ^{[1
]}

Tolmacheva, I. A. ^{[1
]}

Vikharev, Yu. B. ^{[1
]}

Grishko, V. V. ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Tech Chem, Urals Branch, Perm, Russia

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2009年 / 43卷 / 07期

关键词：

Triterpenoids; betulin; beta-enaminoketones; leukocytes;

D O I：

10.1007/s11094-009-0318-8

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The biological activity of several lupane and oleanane beta-enaminoketones was studied. Comparative analysis of leukocyte reactions showed that both groups of triterpene derivatives had high biological activity on chronic administration and that their immunosuppressive activity resulted from toxic effects on lymphocytes.

引用

页码：378 / 380

页数：3