Cu/ITO-Coated Uncladded Fiber-Optic Biosensor Based on Surface Plasmon Resonance

被引:31
作者
Wang, Qi [1 ,2 ]
Sun, Bing [1 ,2 ]
Hu, Ertao [1 ,2 ]
Wei, Wei [1 ,2 ]
机构
[1] Nanjing Univ Posts & Telecommun, Coll Elect & Opt Engn, Nanjing 210023, Jiangsu, Peoples R China
[2] Nanjing Univ Posts & Telecommun, Coll Microelect, Nanjing 210023, Jiangsu, Peoples R China
关键词
Optic fiber sensor; surface plasmon resonance; refractive index; double layers of film; OPTICAL-FIBER; SENSITIVITY-ENHANCEMENT; PHOTONIC CRYSTAL; THIN-FILM; SENSOR; LIQUID;
D O I
10.1109/LPT.2019.2908288
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
A surface plasmon resonance (SPR)-based fiber-optic biosensor with bi-layers (copper, ITO) has been experimentally proposed and demonstrated. Benefitting from its high refractive index and unique optoelectronic properties, the additional ITO layer immobilized onto the Cu film can significantly improve its sensing performance. A sensitivity of 4583.4 nm/RIU (refractive index unit) was achieved, with a large enhancement in the figure of merit (FOM) by 61.6% compared with the sample without the ITO layer. Furthermore, the proposed SPR-based biosensor exhibits a bovine serum albumin (BSA) solution concentration sensitivity of 1.907 nm/(mg/mL) and a detection limit of 5.70x10(-7) mg/mL. Significantly, this biosensor shows a sub-microliter-dose sensitivity, with promising biochemical applications such as DNA hybridization, cancer screenings, medicine examination, and environmental engineering.
引用
收藏
页码:1159 / 1162
页数:4
相关论文
共 25 条
[1]   Surface Plasmon Resonance Biosensors Incorporating Gold Nanoparticles [J].
Bedford, Erin E. ;
Spadavecchia, Jolanda ;
Pradier, Claire-Marie ;
Gu, Frank X. .
MACROMOLECULAR BIOSCIENCE, 2012, 12 (06) :724-739
[2]   Plasmonic nanoshell functionalized etched fiber Bragg gratings for highly sensitive refractive index measurements [J].
Burgmeier, Joerg ;
Feizpour, Amin ;
Schade, Wolfgang ;
Reinhard, Bjoern M. .
OPTICS LETTERS, 2015, 40 (04) :546-549
[3]   Surface plasmon resonance sensors for detection of chemical and biological species [J].
Homola, Jiri .
CHEMICAL REVIEWS, 2008, 108 (02) :462-493
[4]   A surface plasmon resonance hydrogen sensor using Au/Ta2O5/Pd multi-layers on hetero-core optical fiber structures [J].
Hosoki, Ai ;
Nishiyama, Michiko ;
Igawa, Hirotaka ;
Seki, Atsushi ;
Choi, Yongwoon ;
Watanabe, Kazuhiro .
SENSORS AND ACTUATORS B-CHEMICAL, 2013, 185 :53-58
[5]   Universal sensitivity of propagating surface plasmon resonance in nanostructure arrays [J].
Jia, Peipei ;
Yang, Jun .
OPTICS EXPRESS, 2015, 23 (14) :18658-18664
[6]   Sensitivity of optical fiber sensor based on surface plasmon resonance: Modeling and experiments [J].
Kanso, M. ;
Cuenot, S. ;
Louarn, G. .
PLASMONICS, 2008, 3 (2-3) :49-57
[7]   Hollow fiber surface plasmon resonance sensor for the detection of liquid with high refractive index [J].
Liu, Bing-Hong ;
Jiang, Yong-Xiang ;
Zhu, Xiao-Song ;
Tang, Xiao-Li ;
Shi, Yi-Wei .
OPTICS EXPRESS, 2013, 21 (26) :32349-32357
[8]  
Liu C, 2017, OPT EXPRESS, V25, P14227, DOI [10.1364/OE.25.014227, 10.1364/OE.25.014238]
[9]   Optical fiber refractometers based on indium tin oxide coatings fabricated by sputtering [J].
Lopez, S. ;
del Villar, I. ;
Ruiz Zamarreno, C. ;
Hernaez, M. ;
Arregui, F. J. ;
Matias, I. R. .
OPTICS LETTERS, 2012, 37 (01) :28-30
[10]   UiO-66 MOF end-face-coated optical fiber in aqueous contaminant detection [J].
Nazari, Marziyeh ;
Forouzandeh, Mohammad Ali ;
Divarathne, Chamath M. ;
Sidiroglou, Fotios ;
Martinez, Marta Rubio ;
Konstas, Kristina ;
Muir, Benjamin W. ;
Hill, Anita J. ;
Duke, Mikel C. ;
Hill, Matthew R. ;
Collins, Stephen F. .
OPTICS LETTERS, 2016, 41 (08) :1696-1699