Discovery and development of highly potent small-molecule inhibitors of IL-17A

被引:0
作者
Nielsen, S. J. [1 ]
Andersson, J. L. [1 ]
Bengtsson, M. [1 ]
Cowland, S. J. [1 ]
Franch, T. [1 ]
Glad, S. S. [1 ]
Gouliaev, A. H. [1 ]
Jacso, T. [1 ]
Moretti, L. [1 ]
Norager, N. G. [1 ]
Rast, S. [1 ]
Stasi, L. P. [1 ]
Smith, G. P. [1 ]
机构
[1] Nuevolution AS, Copenhagen, Denmark
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
O236
引用
收藏
页码:1810 / 1811
页数:2
相关论文
共 50 条
[41]   The development of small-molecule inhibitors targeting hexokinase 2 [J].
Shan, Wenying ;
Zhou, Yan ;
Tam, Kin Yip .
DRUG DISCOVERY TODAY, 2022, 27 (09) :2574-2585
[42]   Discovery of Small-Molecule Cyclic GMP-AMP Synthase Inhibitors [J].
Padilla-Salinas, Rosaura ;
Sun, Lijun ;
Anderson, Rachel ;
Yang, Xikang ;
Zhang, Shuting ;
Chen, Zhijian J. ;
Yin, Hang .
JOURNAL OF ORGANIC CHEMISTRY, 2020, 85 (03) :1579-1600
[43]   Discovery and characterization of novel small-molecule inhibitors targeting nicotinamide phosphoribosyltransferase [J].
Tian-Ying Xu ;
Sai-Long Zhang ;
Guo-Qiang Dong ;
Xin-Zhu Liu ;
Xia Wang ;
Xiao-Qun Lv ;
Qi-Jun Qian ;
Ruo-Yu Zhang ;
Chun-Quan Sheng ;
Chao-Yu Miao .
Scientific Reports, 5
[44]   Discovery and synthesis of highly potent and selective small molecule inhibitors of the histone methyltransferase EZH2 [J].
Verma, Sharad K. ;
LaFrance, Louis V. ;
Tian, Xinrong ;
Newlander, Ken ;
Duguenne, Celine ;
Suarez, Dominic ;
Knight, Steven D. ;
Burgess, Joelle ;
Brackley, James ;
Johnson, Neil W. ;
Graves, Alan R. ;
Mellinger, Mark ;
Romeril, Stuart ;
Grant, Seth W. ;
Scherzer, Daryl ;
Shu, Art ;
Creasy, Caretha L. ;
Kruger, Ryan ;
Diaz, Elsie ;
Le, Baochau ;
Thompson, Christine ;
Morgan-Ott, Heidi ;
McCabe, Michael T. ;
McHugh, Charles F. ;
Miller, William H. ;
Tummino, Peter ;
Dhanak, Dash .
CANCER RESEARCH, 2012, 72
[45]   A Small-Molecule Screening Platform for the Discovery of Inhibitors of Undecaprenyl Diphosphate Synthase [J].
Czarny, Tomasz L. ;
Brown, Eric D. .
ACS INFECTIOUS DISEASES, 2016, 2 (07) :489-499
[46]   Progress in the Discovery of Small-Molecule Inhibitors of Bromodomain-Histone Interactions [J].
Chung, Chun-Wa ;
Witherington, Jason .
JOURNAL OF BIOMOLECULAR SCREENING, 2011, 16 (10) :1170-1185
[47]   The Structural Evolution of β-Secretase Inhibitors: A Focus on the Development of Small-Molecule Inhibitors [J].
Butini, Stefania ;
Brogi, Simone ;
Novellino, Ettore ;
Campiani, Giuseppe ;
Ghosh, Arun K. ;
Brindisi, Margherita ;
Gemma, Sandra .
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2013, 13 (15) :1787-1807
[48]   Discovery of small-molecule inhibitors of RUVBL1/2 ATPase [J].
Zhang, Gang ;
Wang, Feng ;
Li, Shan ;
Cheng, Kai-Wen ;
Zhu, Yingying ;
Huo, Ran ;
Abdukirim, Elyar ;
Kang, Guifeng ;
Chou, Tsui-Fen .
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 62
[49]   Small-molecule caspase inhibitors [J].
Zhenodarova, S. M. .
RUSSIAN CHEMICAL REVIEWS, 2010, 79 (02) :119-143
[50]   Novel Dual Small-Molecule HIV inhibitors: Scaffolds and Discovery Strategies [J].
Song, Anran ;
Yu, Haiqing ;
Wang, Changyuan ;
Zhu, Xingqi ;
Liu, Kexin ;
Ma, Xiaodong .
CURRENT PHARMACEUTICAL DESIGN, 2015, 21 (07) :950-962