INS-eGFP transgenic pigs: a novel reporter system for studying maturation, growth and vascularisation of neonatal islet-like cell clusters

被引:22
作者
Kemter, Elisabeth [1 ,2 ]
Cohrs, Christian M. [3 ,4 ,5 ]
Schaefer, Matthias [6 ]
Schuster, Marion [7 ]
Steinmeyer, Klaus [6 ]
Wolf-van Buerck, Lelia [7 ]
Wolf, Andrea [6 ]
Wuensch, Annegret [1 ,2 ]
Kurome, Mayuko [1 ,2 ]
Kessler, Barbara [1 ,2 ]
Zakhartchenko, Valeri [1 ,2 ]
Loehn, Matthias [6 ]
Ivashchenko, Yuri [6 ]
Seissler, Jochen [7 ]
Schulte, Anke M. [6 ]
Speier, Stephan [3 ,4 ,5 ]
Wolf, Eckhard [1 ,2 ,5 ]
机构
[1] Ludwig Maximilians Univ Munchen, Gene Ctr, Chair Mol Anim Breeding & Biotechnol, Feodor Lynen Str 25, D-81377 Munich, Germany
[2] Ludwig Maximilians Univ Munchen, CiMM, Munich, Germany
[3] Tech Univ Dresden, Univ Clin Carl Gustav Carus, Helmholtz Zentrum Munchen, Helmholtz Zentrum Munich,PLID, Neuherberg, Germany
[4] Tech Univ Dresden, DFG Ctr Regenerat Therapies Dresden CRTD, Fac Med, Dresden, Germany
[5] German Ctr Diabet Res DZD, Neuherberg, Germany
[6] Sanofi Aventis Deutschland GmbH, Diabet Div, Frankfurt, Germany
[7] Ludwig Maximilians Univ Munchen, Klinikum Ludwig Maximilians Univ, Med Clin Campus Innenstadt, Med Klin & Poliklin 4,Diabet Ctr, Munich, Germany
关键词
Islet maturation; Pig; Reporter gene; Xenotransplantation; ONSET; MASS;
D O I
10.1007/s00125-017-4250-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1152 / 1156
页数:5
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