Management of Rhabdomyosarcoma in Pediatric Patients

被引:11
作者
Rogers, Timothy N. [1 ]
Dasgupta, Roshni [2 ]
机构
[1] Univ Hosp Bristol NHS Fdn Trust, Dept Pediat Surg, Bristol, Avon, England
[2] Univ Cincinnati, Cincinnati Childrens Hosp Med Ctr, Div Pediat Gen & Thorac Surg, 3333 Burnet Ave, Cincinnati, OH 45229 USA
关键词
Rhabdomyosarcoma; Pediatric; Soft tissue sarcoma; Surgery;
D O I
10.1016/j.soc.2020.11.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Treatment of RMS involves a multimodality approach including chemotherapy, surgery, and RT while minimizing the long-term treatment-related morbidities. This article outlines the key points related to the diagnosis and management of RMS with a focus on current surgical management of RMS at specific tumor sites. There is a need for improved RT and surgical techniques as well as systemic therapy in RMS to reduce locoregional and metastatic relapse, reduce late sequelae of treatment, and improve functional outcomes. Better understanding of the biology of the RMS subtypes found in adult patients, with increased enrollment into cooperative group studies, is required.
引用
收藏
页码:339 / 353
页数:15
相关论文
共 67 条
[1]   Does bladder preservation (as a surgical principle) lead to retaining bladder function in bladder/prostate rhabdomyosarcoma? Results from Intergroup Rhabdomyosarcoma Study IV [J].
Arndt, C ;
Rodeberg, D ;
Breitfeld, PP ;
Raney, RB ;
Ullrich, F ;
Donaldson, S .
JOURNAL OF UROLOGY, 2004, 171 (06) :2396-2403
[2]   Medical Progress - Common musculoskeletal tumors of childhood and adolescence [J].
Arndt, CAS ;
Crist, WM .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (05) :342-352
[3]   Sentinel lymph node mapping using indocyanine green in patients with uterine and cervical neoplasms: restrictions of the method [J].
Bedynska, M. ;
Szewczyk, G. ;
Klepacka, T. ;
Sachadel, K. ;
Maciejewski, T. ;
Szukiewicz, D. ;
Fijalkowska, A. .
ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2019, 299 (05) :1373-1384
[4]   Outcome of 449 adult patients with rhabdomyosarcoma: an observational ambispective nationwide study [J].
Bompas, Emmanuelle ;
Campion, Loic ;
Italiano, Antoine ;
Le Cesne, Axel ;
Chevreau, Christine ;
Isambert, Nicolas ;
Toulmonde, Maud ;
Mir, Olivier ;
Ray-Coquard, Isabelle ;
Piperno-Neumann, Sophie ;
Saada-Bouzid, Esma ;
Rios, Maria ;
Kurtz, Jean-Emmanuel ;
Delcambre, Corinne ;
Dubray-Longeras, Pascale ;
Duffaud, Florence ;
Karanian, Marie ;
Le Loarer, Francois ;
Soulie, Patrick ;
Penel, Nicolas ;
Blay, Jean-Yves .
CANCER MEDICINE, 2018, 7 (08) :4023-4035
[5]   Fertility Preservation Options in Pediatric and Adolescent Patients With Cancer [J].
Burns, Karen C. ;
Hoefgen, Holly ;
Strine, Andrew ;
Dasgupta, Roshni .
CANCER, 2018, 124 (09) :1867-1876
[6]  
Canal F, 2007, CURR DIAGN PATHOL, V13, P150
[7]   Primary re-excision: the Italian experience in patients with localized soft-tissue sarcomas [J].
Cecchetto, G ;
Guglielmi, M ;
Inserra, A ;
Zanetti, I ;
Dall'Igna, P ;
Gigante, C ;
Carli, M .
PEDIATRIC SURGERY INTERNATIONAL, 2001, 17 (07) :532-534
[8]   Biopsy or debulking surgery as initial surgery for locally advanced rhabdomyosarcomas in children? The experience of the Italian cooperative group studies [J].
Cecchetto, Giovanni ;
Bisogno, Gianni ;
De Corti, Federica ;
Dall'lgna, Patrizia ;
Inserra, Alessandro ;
Ferrari, Andrea ;
Garaventa, Alberto ;
Scagnellato, Angela ;
Carli, Modesto .
CANCER, 2007, 110 (11) :2561-2567
[9]   Current and Future Treatment Strategies for Rhabdomyosarcoma [J].
Chen, Celine ;
Garcia, Heathcliff Dorado ;
Scheer, Monika ;
Henssen, Anton G. .
FRONTIERS IN ONCOLOGY, 2019, 9
[10]   Widespread intratumoral virus distribution with fractionated injection enables local control of large human rhabdomyosarcoma xenografts by oncolytic herpes simplex viruses [J].
Currier, MA ;
Adams, LC ;
Mahller, YY ;
Cripe, TP .
CANCER GENE THERAPY, 2005, 12 (04) :407-416