The Development of the Human Microbiome Why Moms Matter

被引:18
作者
Chu, Derrick M. [1 ]
Valentine, Gregory C. [1 ]
Seferovic, Maxim D. [1 ]
Aagaard, Kjersti M. [1 ]
机构
[1] Div Maternal Fetal Med, Dept Obstet & Gynecol, 1 Baylor Plaza, Houston, TX 77030 USA
关键词
Microbiome; Mode of delivery; Development; HIGH-FAT DIET; ENDOMETRIAL MICROBIOTA; INTESTINAL MICROBIOTA; TEMPORAL DEVELOPMENT; ORAL BACTERIA; BREAST-MILK; INFANTS; IMPACT; MODE; LACTATION;
D O I
10.1016/j.gtc.2019.04.004
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The human body is cohabitated with trillions of commensal bacteria that are essential for our health. However, certain bacteria can also cause diseases in the human host. Before the microbiome can be attributed to disease risk and pathogenesis, normal acquisition and development of the microbiome must be understood. Here, we explore the evidence surrounding in utero microbial exposures and the significant of this exposure in the proper development of the fetal and neonatal microbiome. We further explore the development of the fetal and neonatal microbiome and its relationship to preterm birth, feeding practices, and mode of delivery, and maternal diet.
引用
收藏
页码:357 / +
页数:20
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