Recent highlights of biosynthetic studies on marine natural products

被引：25
|
作者：
Amiri Moghaddam, Jamshid [1 ]
Jautzus, Theresa [1 ]
Alanjary, Mohammad [2 ]
Beemelmanns, Christine [1 ]
机构：
[1] Leibniz Inst Nat Prod Res & Infect Biol HKI, Jr Res Grp Chem Biol Microbe Host Interact, Beutenbergstr 11a, D-07745 Jena, Germany
[2] Wageningen Univ, Bioinformat Grp, Wageningen, Netherlands
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2021年 / 19卷 / 01期
基金：
欧洲研究理事会;
关键词：
UNSATURATED FATTY-ACIDS; SECONDARY METABOLITES; NONRIBOSOMAL PEPTIDE; GENE-CLUSTER; THIOCORALINE; THIOMARINOL; SIDEROPHORES; FERMENTATION; INSIGHTS; PATHWAYS;
D O I：
10.1039/d0ob01677b
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Marine bacteria are excellent yet often underexplored sources of structurally unique bioactive natural products. In this review we cover the diversity of marine bacterial biomolecules and highlight recent studies on structurally novel natural products. We include different compound classes and discuss the latest progress related to their biosynthetic pathway analysis and engineering: examples range from fatty acids over terpenes to PKS, NRPS and hybrid PKS-NRPS biomolecules.
引用
收藏
页码：123 / 140
页数：18
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