Efficient and direct synthesis of poly-substituted indeno[1,2-b]quinolines assisted by p-toluene sulfonic acid using high-temperature water and microwave heating via one-pot, three-component reaction

被引：75

作者：

Tu, Shu-Jiang ^{[1
]}

Jiang, Bo ^{[1
]}

Zhang, Jun-Yong ^{[1
]}

Jia, Run-Hong ^{[1
]}

Zhang, Yan ^{[1
]}

Yao, Chang-Sheng ^{[1
]}

机构：

[1] Xuzhou Normal Univ, Key Lab Biotechnol Med Plants, Dept Chem, Xuzhou 211116, Jiangsu, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2006年 / 4卷 / 21期

关键词：

D O I：

10.1039/b611462h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reactions of aldehydes, 1,3-indanedione and enaminones were successfully carried out using p-toluene sulfonic acid (p-TsOH) as a catalyst and high-temperature water as a solvent under microwave irradiation. This method provided several advantages such as rapid reaction times, high yields, and a simple workup procedure. In addition, a possible mechanism to account for the reaction was proposed.

引用

页码：3980 / 3985

页数：6

共 47 条

[31] Biradicals/zwitterions from enallene-isonitriles.: Formal [4+1] cycloadditions leading to 11H-indeno[1,2-b]quinoline and related compounds [J].