C-type natriuretic peptide

被引:112
作者
Barr, CS [1 ]
Rhodes, P [1 ]
Struthers, AD [1 ]
机构
[1] UNIV DUNDEE,NINEWELLS HOSP & MED SCH,DEPT PHARMACOL & CLIN PHARMACOL,DUNDEE DD1 9SY,SCOTLAND
关键词
atrial natriuretic peptide; B-type natriuretic peptide; C-type natriuretic peptide; vascular natriuretic peptide system;
D O I
10.1016/S0196-9781(96)00110-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
C-type natriuretic peptide is a 22-amino acid peptide that was initially identified in the central nervous system. The distribution of C-type natriuretic peptide, which has structural homology with atrial and brain natriuretic peptides, is wide and includes the endothelium, myocardium, gastrointestinal, and genitourinary tracts. The biological effects of this peptide are being elucidated in a number of sites in a number of species; however, the novel endothelial site of production of C-type natriuretic peptide and the proximal situation of its receptor in vascular smooth muscle suggest that this vascular natriuretic peptide system may play a role in concert with other local systems in the control of vascular tone. Copyright (C) 1996 Elsevier Science Inc.
引用
收藏
页码:1243 / 1251
页数:9
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