Hematological manifestations of rheumatoid arthritis

被引:66
作者
Bowman, SJ [1 ]
机构
[1] Univ Birmingham, Sch Med, Dept Rheumatol, Div Immun & Infect, Birmingham B15 2TT, W Midlands, England
关键词
rheumatoid arthritis; hematological; Felty's syndrome;
D O I
10.1080/030097402760375124
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To inform clinical rheumatologists about the common and rarer hematological manifestations of rheumatoid arthritis with an emphasis on diagnosis and therapy and a particular reference to Felty's syndrome. Methods: Literature review. Results: The hematological manifestations can be conveniently categorized into the broad areas of; anemia, particularly NSAID induced iron deficiency anemia and the anemia of chronic disease; neutropenia, particularly Felty's syndrome and the large granular lymphocyte syndrome and drug induced neutropenia; thrombocytopenia, particularly autoimmune and drug induced thrombocytopenia; and hematological malignancy. Rarer conditions, their diagnosis and therapy are also described in this review. Conclusion: Hematological manifestations of rheumatoid arthritis are very common. A logical approach using easily available tests should allow straightforward decisions about diagnosis and therapy to be made, even in patients with some of the rarer manifestations.
引用
收藏
页码:251 / 259
页数:9
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