A convenient method for the preparation of tuberculostatic diacylhydrazines

被引：0
作者：
Hearn, MJ
Kang, HJO
Thai, M
机构：
来源：
BULLETIN DES SOCIETES CHIMIQUES BELGES | 1997年 / 106卷 / 02期
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中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
1-Isonicotinoyl-2-acylhydrazines (II), which display activity against Mycobacterium tuberculosis, may be readily prepared in good yields and high purity from the reactions of isonicotinic acid hydrazide with carboxylic anhydrides in ether. The progress of the reactions can be followed opportunely by significant changes in the mid-range infrared spectra and near-infrared spectra, permitting reliable characterization.
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页码：109 / 114
页数：6
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