Carotid Magnetic Resonance Imaging - A Window to Study Atherosclerosis and Identify High-Risk Plaques

被引：26

作者：

Oikawa, Minako ^{[2
]}

Ota, Hideki ^{[4
]}

Takaya, Norihide ^{[3
]}

Miller, Zach ^{[5
]}

Hatsukami, Thomas S. ^{[5
]}

Yuan, Chun ^{[1
,5
]}

机构：

[1] Univ Washington, Vasc Imaging Lab, Dept Radiol, Seattle, WA 98195 USA

[2] Tohoku Univ, Grad Sch Med, Dept Cardiovasc Med, Sendai, Miyagi 980, Japan

[3] Juntendo Univ, Sch Med, Dept Cardiovasc Med, Tokyo 113, Japan

[4] Michigan State Univ, Dept Radiol, E Lansing, MI 48824 USA

[5] Univ Washington, Dept Surg, Seattle, WA 98195 USA

来源：

CIRCULATION JOURNAL | 2009年 / 73卷 / 10期

关键词：

Atherosclerosis; Cardiovascular diseases; Carotid arteries; Imaging; Magnetic resonance imaging; INTIMA-MEDIA THICKNESS; CELL-ADHESION MOLECULE-1; CORONARY-ARTERY-DISEASE; LIPID-LOWERING THERAPY; RICH NECROTIC CORE; IN-VIVO ACCURACY; BLACK-BLOOD MRI; HIGH-RESOLUTION; FIBROUS CAP; INTRAPLAQUE HEMORRHAGE;

D O I：

10.1253/circj.CJ-09-0617

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Despite recent advances in the understanding and etiology of cardiovascular disease, it remains the leading cause of morbidity and mortality worldwide. A great deal of research has been dedicated to investigating and identifying plaque instability: the so-called "vulnerable plaque". A reliable, in vivo, imaging method capable of identifying plaque characteristics associated with high-risk plaque will be immensely useful for evaluating plaque status and predicting future events. With excellent soft-tissue contrast and resolution, magnetic resonance imaging (MRI) has the ability to visualize features of vulnerable plaques, as well as perform longitudinal studies on the etiology, progression, and regression of atherosclerotic plaque. This review will cover the current state-of-the-art and new developments in carotid MRI to characterize atherosclerosis and its use in clinical diagnoses and longitudinal studies to understand mechanisms of lesion progression and regression. (Circ J 2009; 73: 1765-1773)

引用

页码：1765 / 1773

页数：9

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