Selective inhibition of TNF-α and IL-1β do not affect E-coli-induced inflammation in human whole blood, in contrast to combined complement- and CD14-inhibition

被引：0
|
作者：
Barratt-Due, Andreas
Thorgersen, Ebbe B.
Lindstad, Julie
Pharo, Anne
Brekke, Ole-Lars
Christiansen, Dorte
Lambris, John D.
Mollnes, Tom E.
机构：
来源：
MOLECULAR IMMUNOLOGY | 2009年 / 46卷 / 14期
关键词：
D O I：
10.1016/j.molimm.2009.05.241
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：2838 / 2838
页数：1
相关论文
共 18 条
  • [1] Selective inhibition of TNF-α or IL-1β does not affect E. coli-induced inflammation in human whole blood
    Barratt-Due, Andreas
    Thorgersen, Ebbe Billmann
    Lindstad, Julie K.
    Pharo, Anne
    Brekke, Ole-Lars
    Christiansen, Dorte
    Lambris, John D.
    Mollnes, Tom Eirik
    MOLECULAR IMMUNOLOGY, 2010, 47 (09) : 1774 - 1782
  • [2] Inhibition of complement and CD14 efficiently inhibits a broad panel of E-coli-induced inflammatory reactions in human whole blood
    Brekke, Ole-Lars
    Christiansen, Dorte
    Fure, Hilde
    Fung, Michael
    Mollnes, Tom E.
    MOLECULAR IMMUNOLOGY, 2007, 44 (16) : 3925 - 3925
  • [3] Combined inhibition of complement and CD14 abolish E-coli-induced cytokine-, chemokine- and growth factor-synthesis in human whole blood
    Brekke, Ole-Lars
    Christiansen, Dorte
    Fure, Hilde
    Pharo, Anne
    Fung, Michael
    Riesenfeld, Johan
    Mollnes, Tom Eirik
    MOLECULAR IMMUNOLOGY, 2008, 45 (14) : 3804 - 3813
  • [4] The Effects of Selective Complement and CD14 Inhibition on the E-coli-Induced Tissue Factor mRNA Upregulation, Monocyte Tissue Factor Expression, and Tissue Factor Functional Activity in Human Whole Blood
    Brekke, O. -L.
    Waage, C.
    Christiansen, D.
    Fure, H.
    Qu, H.
    Lambris, John D.
    Osterud, B.
    Nielsen, E. W.
    Mollnes, T. E.
    COMPLEMENT THERAPEUTICS, 2013, 735 : 123 - 136
  • [5] Effects of combined complement complement and CD14 inhibition on Escherichia coli-induced thromboinflammation in human whole blood in the presence and absence of antibiotics
    Joakimsen, Ingrid Sofie
    Karlsen, Bard Ove
    Emblem, Ase Eeg
    Pettersen, Kristin
    Gronli, Renate Henriksen
    Mollnes, Tom Erik
    Brekke, Ole-Lars
    IMMUNOBIOLOGY, 2023, 228 (05) : 97 - 97
  • [6] Comparison of Eritoran with a neutralizing anti-CD14 antibody combined with complement inhibition on bacteria-induced inflammation in human whole blood
    Gustavsen, Alice
    Nymo, Stig
    Espevik, Terje
    Mollnes, Tom Eirik
    MOLECULAR IMMUNOLOGY, 2015, 67 (01) : 140 - 141
  • [7] An ex vivo posttreatment model of sepsis: Effect on inflammation by adding complement- and CD14-inhibitors after E. coli to human whole blood
    Egge, Kjetil H.
    Thorgersen, Egge B.
    Lindstad, Julie K.
    Pharo, Anne M.
    Barratt-Due, Andreas
    Mollnes, Tom E.
    IMMUNOBIOLOGY, 2012, 217 (11) : 1137 - 1138
  • [8] The effect of combined inhibition of C5aR1 and CD14 on phagocytosis of E. coli in human whole blood
    Christiansen, Dorte
    Skjeflo, Espen Waage
    Landsem, Anne
    Mathisen, Monica Dammen
    Fure, Hilde
    Stenvik, Jorgen
    Woodruff, Trent
    Espevik, Terje
    Mollnes, Tom Eirik
    IMMUNOBIOLOGY, 2016, 221 (10) : 1220 - 1220
  • [9] Combined Inhibition of Complement and CD14 Efficiently Attenuated the Inflammatory Response Induced by Staphylococcus aureus in a Human Whole Blood Model
    Skjeflo, Espen W.
    Christiansen, Dorte
    Espevik, Terje
    Nielsen, Erik W.
    Mollnes, Tom E.
    JOURNAL OF IMMUNOLOGY, 2014, 192 (06): : 2857 - 2864
  • [10] Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model
    Skjeflo, Espen
    Christiansen, Dorte
    Lambris, John D.
    Espevik, Terje
    Nielsen, Erik Waage
    Mollnes, Tom Eirik
    IMMUNOBIOLOGY, 2012, 217 (11) : 1152 - 1153
12