Bone marrow transplantation does not correct the hyper IgE syndrome

被引：75

作者：

Gennery, AR ^{[1
]}

Flood, TJ ^{[1
]}

Abinun, M ^{[1
]}

Cant, AJ ^{[1
]}

机构：

[1] Newcastle Gen Hosp, Dept Pediat Immunol, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England

来源：

BONE MARROW TRANSPLANTATION | 2000年 / 25卷 / 12期

关键词：

hyper Ige syndrome; bone marrow transplantation;

D O I：

10.1038/sj.bmt.1702446

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Congenital immunodeficiency in hyper IgE syndrome is characterised by a markedly raised IgE level, recurrent staphylococcal skin infection and pneumatoceles. Standard treatments include anti-staphylococcal antibiotics. We report a severely affected patient in whom successful bone marrow transplantation was followed by reappearance of the immunodeficiency. We conclude that bone marrow transplantation does not cure the immunological features of the hyper IgE syndrome.

引用

页码：1303 / 1305

页数：3

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