Navigating the signalling network in mouse cardiac myocytes

被引：72

作者：

Sambrano, GR

Fraser, I

Han, HP

Ni, Y

O'Connell, T

Yan, Z

Stull, JT

机构：

[1] Univ Calif San Francisco, Dept Mol & Cellular Pharmacol, San Francisco, CA 94143 USA

[2] CALTECH, Div Biol, Pasadena, CA 91125 USA

[3] Univ Texas, SW Med Ctr, Dept Pharmacol, Dallas, TX 75390 USA

[4] Univ Texas, SW Med Ctr, Dept Physiol, Dallas, TX 75390 USA

[5] San Francisco Vet Adm Med Ctr, Dept Cardiol, San Francisco, CA 94121 USA

来源：

NATURE | 2002年 / 420卷 / 6916期

关键词：

D O I：

10.1038/nature01306

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Cardiac myocytes have a complex network of signals that regulates their essential role in the rhythmic pumping of the heart. This network is an appealing model system in which to study the basic principles underlying cellular signalling mechanisms. Progress in this effort has come through the establishment of standardized myocyte isolation and culture procedures and characterization of important signalling responses.

引用

收藏

页码：712 / 714

页数：3

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