Bioactive compounds: Definition and assessment of activity

被引:202
作者
Biesalski, Hans-Konrad [1 ]
Dragsted, Lars Ove [2 ]
Elmadfa, Ibrahim [3 ]
Grossklaus, Rolf [4 ]
Muller, Michael [5 ]
Schrenk, Dieter [6 ]
Walter, Paul [7 ]
Weber, Peter [8 ]
机构
[1] Univ Hohenheim, Dept Biol Chem & Nutr, D-7000 Stuttgart, Germany
[2] Danish Vet & Food Adm, Inst Food Safety & Nutr, Soborg, Denmark
[3] Univ Vienna, Inst Nutr Sci, Vienna, Austria
[4] Bundesinst Gesundheitlichen Verbraucherschutz & V, Fed Inst Consumer Hlth Protect & Vet Med, Berlin, Germany
[5] Agr Univ Wageningen, Div Human Nutr & Epidemiol, Wageningen, Netherlands
[6] Univ Kaiserslautern, Dept Food Chem & Environm Toxicol, Kaiserslautern, Germany
[7] Univ Basel, Novartis Forsch Stiftung, Inst Biomed Res, Basel, Switzerland
[8] Hoffmann La Roche Vitamins Ltd, Res & Dev Human Nutr & Hlth, Basel, Switzerland
关键词
Biomarker; Bioactive constituents; Nutraceuticals; Health effect; Xenobiotics; Bioavailability; Intake; Phytochemicals; RISK-FACTOR;
D O I
10.1016/j.nut.2009.04.023
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Biomarkers and their role in evaluating efficacy and safety were the topic of the 23rd Hohenheim Consensus Meeting at the University of Hohenheim in Stuttgart. Scientists who had published and reviewed scientific and regulatory papers on the topic were invited, among them basic researchers, toxicologists, clinicians, and nutritionists. The participants were presented with 11 questions (in bold font), which were discussed and answered (in italic font) at the workshop, with the aim of summarizing the current state of knowledge on the subject. The explicatory text accompanying the short answers was produced and agreed on after the conference and was backed up by corresponding references. (C) 2009 Published by Elsevier Inc.
引用
收藏
页码:1202 / 1205
页数:4
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