Feasibility Study of Microsecond Pulsed Microwave Ablation Using a Minimally Invasive Antenna

被引:11
作者
Evans, Audrey L. [1 ]
Sawicki, James F. [1 ]
Hung Luyen [1 ,2 ]
Mohtashami, Yahya [1 ,3 ]
Behdad, Nader [1 ]
Hagness, Susan C. [1 ]
机构
[1] Univ Wisconsin, Dept Elect & Comp Engn, Madison, WI 53706 USA
[2] Univ North Texas, Dept Elect Engn, Denton, TX 76203 USA
[3] Univ Calif Santa Barbara, Santa Barbara, CA 93106 USA
来源
IEEE ANTENNAS AND WIRELESS PROPAGATION LETTERS | 2021年 / 20卷 / 04期
基金
美国国家科学基金会;
关键词
Microwave antennas; Microwave imaging; Microwave theory and techniques; Electromagnetic heating; Microwave integrated circuits; Microwave FET integrated circuits; Liver; Microwave ablation (MWA); thermal therapy;
D O I
10.1109/LAWP.2021.3059530
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
In this letter, we established the feasibility of producing localized ablation zones using microsecond pulsed microwave ablation (MWA) as an alternative to conventional continuous wave (CW) MWA. We verified that a thin floating-sleeve dipole ablation probe can withstand pulsed power delivery with peak powers as high as 25 kW, with pulsewidth on the order of 1 mu s. We conducted MWA experiments in egg white using CW and pulsed modes of operation and found that ablation zones achieved via pulsed MWA are comparable in dimension to those created via CW MWA when the average power and procedure duration are equivalent. Finally, we performed pulsed MWA experiments in bovine liver and confirmed that pulsed MWA consistently produces large, localized ablation zones and temperatures that exceed 100 degrees C. Establishing the feasibility of pulsed MWA opens the opportunity for developing a coupled MWA treatment and imaging system using pulsed MWA and microwave-induced thermoacoustic signals for real-time monitoring of MWA.
引用
收藏
页码:627 / 631
页数:5
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