Osimertinib Overcomes Alectinib Resistance Caused by Amphiregulin in a Leptomeningeal Carcinomatosis Model of EML4-ALK Lung Cancer

被引:0
|
作者
Arai, S. [1 ]
Takeuchi, S. [1 ]
Fukuda, K. [1 ]
Nishiyama, A. [1 ]
Tanimoto, A. [1 ]
Taniguchi, H. [1 ]
Satouchi, M. [2 ]
Nanjo, S. [1 ]
Katayama, R. [3 ]
Nishio, M. [4 ]
Zheng, M. [5 ]
Wu, Y. [6 ,7 ]
Yano, S. [1 ]
机构
[1] Kanazawa Univ, Canc Res Inst, Kanazawa, Ishikawa, Japan
[2] Hyogo Canc Ctr, Akashi, Hyogo, Japan
[3] Japanese Fdn Canc Res, Canc Chemotherapy Ctr, Tokyo, Japan
[4] Japanese Fdn Canc Res, Canc Inst Hosp, Tokyo, Japan
[5] Guangdong Lung Canc Inst, Guangzhou, Guangdong, Peoples R China
[6] Guangdong Prov Peoples Hosp, Guangdong Lung Canc Inst, Guangzhou, Guangdong, Peoples R China
[7] Guangdong Acad Med Sci, Guangzhou, Guangdong, Peoples R China
关键词
leptomeningeal carcinomatosis; alectinib resistance; Osimertinib;
D O I
10.1016/j.jtho.2019.08.1841
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P2.14-56
引用
收藏
页码:S852 / S853
页数:2
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