Wheat-dependent, exercise-induced anaphylaxis

被引：0

作者：

Brans, R. ^{[1
]}

Ott, H. ^{[1
]}

Merk, H. F. ^{[1
]}

机构：

[1] Univ Klinikum RWTH Aachen, Klin Allergol & Dermatol, D-52074 Aachen, Germany

来源：

HAUTARZT | 2009年 / 60卷 / 12期

关键词：

Wheat; Exercise; Anaphylaxis; Omega-5-Gliadin; IgE; DIAGNOSIS; ALLERGENS; PEPTIDES;

D O I：

10.1007/s00105-009-1875-1

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Wheat-dependent exercise-induced anaphylaxis (WDEIA) is a rare IgE-dependent anaphylaxis to wheat, which occurs in sensitized people after ingestion of wheat followed by physical exercise. The major allergen associated with WDEIA is the wheat protein Omega (omega)-5-Gliadin (Tri a 19). We present three cases of WDEIA, demonstrating that this disease might be more frequent than anticipated and that neither prick test nor specific IgE to allergen extracts but rather detection of specific IgE against the recombinant protein Tri a 19 leads to diagnosis.

引用

页码：956 / +

页数：4

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