Monocyte TREM-1 membrane expression in non-infectious inflammation

被引:20
作者
Cavaillon, Jean-Marc [1 ]
机构
[1] Inst Pasteur, Unit Cytokines & Inflammat, F-75015 Paris, France
关键词
MYELOID CELLS-1; ACUTE-PANCREATITIS; IMMUNE-RESPONSE;
D O I
10.1186/cc7882
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Sterile or non-infectious inflammation and severe infection are accompanied by very similar events. Damage (or danger)-associated molecular patterns and pathogen-associated molecular patterns trigger the release of inflammatory mediators and modulate the expression of cell surface receptors. The increased expression on monocytes and neutrophils of triggering receptor expressed on myeloid cells 1 is a hallmark of both infectious and non-infectious inflammation.
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页数:2
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