A greener synthetic protocol for the preparation of carbodiimide

被引：84

作者：

Ali, Abdur Rezzak ^{[1
]}

Ghosh, Harisadhan ^{[1
]}

Patel, Bhisma K. ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Gauhati 781039, Assam, India

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 07期

关键词：

USEFUL REAGENT; ISOCYANATES; ISOTHIOCYANATES; COMPLEXES; CHEMISTRY; CHLORIDE; CRYSTAL; AMINES;

D O I：

10.1016/j.tetlet.2009.12.017

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new and facile preparation of symmetrical and unsymmetrical 1,3-diaryl and aryl-alkyl carbodiimides via a dehydrosulfurisation of their corresponding thioureas is described. Herein, the classical method of oxidative desulfurisation of thiourea to carbodiimide involving toxic heavy metal oxides (HgO) has been replaced with an easily available, cost-effective and environmentally benign reagent, iodine. Simple reaction conditions, easy purification of the products and high yields are important attributes of the present methodology and perhaps the best alternative from a green chemistry perspective. The only limitation to this method however, is in the preparation of 1,3-dialkyl Substituted carbodiimide. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：1019 / 1021

页数：3

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