Radiochemical separation of 88Y from a SrCl2 target using chelating resin Chelex 100

被引:15
作者
Aardaneh, K. [1 ]
Perrang, C. [1 ]
Dolley, S. [1 ]
van der Meulen, N. [1 ]
van der Walt, T. N. [1 ]
机构
[1] iThemba LABS, ZA-7129 Somerset W, South Africa
关键词
D O I
10.1007/s10967-006-0474-1
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Yttrium-88 was produced from irradiation of a SrCl2 target (4.8 g, pressed into a 19 mm disc) by 33 MeV proton beam at a current of up to 90 mA. Chelating resin Chelex 100 (H+ form, 100-200 mesh) was used for the separation of yttrium radionuclides (including Y-88) from strontium. 0.01M nitric acid was used for the dissolution of target (100 ml), retention of Y and elution of Sr (200 ml). For the elution of yttrium, 25 ml 1M HNO3 was employed. The column was 4 cm long with internal diameter of 1.6 cm. The flow rate was 1 ml/min throughout the separation procedure. The Y-88 recovery yield was 94% average and the stable Sr content in the final product (5 ml 0.1M HCl) was estimated to be less than 3 ppm.
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收藏
页码:641 / 643
页数:3
相关论文
共 12 条
[1]   Some nuclear chemical aspects of medical generator nuclide production at the Los Alamos hot cell facility [J].
Fassbender, M ;
Nortier, FM ;
Phillips, DR ;
Hamilton, VT ;
Heaton, RC ;
Jamriska, DJ ;
Kitten, JJ ;
Pitt, LR ;
Salazar, LL ;
Valdez, FO ;
Peterson, EJ .
RADIOCHIMICA ACTA, 2004, 92 (4-6) :237-243
[2]  
GANSOW O A, 1989, Journal of Labelled Compounds and Radiopharmaceuticals, V26, P290
[3]  
GOODWIN DA, 1994, CANCER RES, V54, P5937
[4]  
Griffiths GL, 2003, J NUCL MED, V44, P77
[5]  
IYER SG, 1976, INDIAN J CHEM A, V14, P437
[6]   SUBSTOICHIOMETRIC DETERMINATION OF YTTRIUM IN SUPERCONDUCTING OXIDE CERAMICS BY MEANS OF CARRIER-FREE RADIOISOTOPE ADDITION [J].
KATOH, M ;
SHIGEMATSU, T ;
SHIKANO, K ;
YONEZAWA, H .
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-LETTERS, 1987, 119 (04) :237-246
[7]   Radiochemical studies relevant to the production of 86Y and 88Y at a small-sized cyclotron [J].
Kettern, K ;
Linse, KH ;
Spellerberg, S ;
Coenen, HH ;
Qaim, SM .
RADIOCHIMICA ACTA, 2002, 90 (12) :845-849
[8]   MEASUREMENTS OF THE THERMAL-NEUTRON CROSS-SECTION OF 90SR(N,GAMMA)91SR REACTION [J].
LONE, MA ;
EDWARDS, WJ ;
COLLINS, R .
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1993, 332 (1-2) :232-238
[9]   Electrochemical separation and purification of yttrium-86 [J].
Reischl, G ;
Rösch, F ;
Machulla, HJ .
RADIOCHIMICA ACTA, 2002, 90 (04) :225-228
[10]   PRODUCTION OF THE POSITRON EMITTING RADIOISOTOPE-Y-86 FOR NUCLEAR MEDICAL APPLICATION [J].
ROSCH, F ;
QAIM, SM ;
STOCKLIN, G .
APPLIED RADIATION AND ISOTOPES, 1993, 44 (04) :677-681