Leiomyosarcoma: Clinicopathological study and retrospective analysis of prognostic factors in a series of 100 patients

被引：4
作者：
Muratori, Francesco [1 ]
Greto, Daniela [3 ]
Cenatiempo, Mauro [1 ]
Mazzei, Giacomo [1 ]
Frenos, Filippo [1 ]
Roselli, Giuliana [2 ]
Livi, Lorenzo [3 ]
Capanna, Rodolfo [4 ]
Baldi, Giacomo [4 ]
Campanacci, Domenico Andrea [1 ]
机构：
[1] Azienda Osped Univ Careggi Firenze, Div Ortopedia Oncol & Ricostrutt, Florence, Italy
[2] Azienda Osped Univ Careggi Firenze, Div Radiol, Florence, Italy
[3] Azienda Osped Univ Careggi Firenze, Unita Radioterapia, Florence, Italy
[4] Osped Prato, Div Oncol, Prato, Italy
来源：
JOURNAL OF ORTHOPAEDICS | 2019年 / 16卷 / 04期
关键词：
Leiomyosarcoma; Size; Age; Recurrence; Metastasis; SOFT-TISSUE SARCOMA; LOCAL RECURRENCE; RADIATION-THERAPY; SURGICAL MARGINS; EXTREMITIES; SURVIVAL;
D O I：
10.1016/j.jor.2019.03.004
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
The Authors reported a retrospective study of 100 Leiomyosarcoma (LMS), evaluating factors that may influence Overall Survival (OS), Local Recurrence Free Survival (LRFS), Metastasis Free Survival (MFS). Tumor Size (P= 0,0009), Local Recurrence (P= 0,0487), Distant relapse (P < 0,0001), Type of Presentation (P= 0,0213) were significant risk factors affecting overall survival (OS). Tumor Size (P= 0.024), age at diagnosis (P= 0,0086), type of presentation (P < 0,0001) and Local Recurrence (P= 0.0152) affected metastasis free survival (MFS). Type of presentation (P= 0,001) was an independent prognostic factor of local recurrence-free survival (LRFS).
引用
收藏
页码：303 / 307
页数：5
相关论文
共 25 条
  • [1] Outcomes and Prognostic Factors for a Consecutive Case Series of 115 Patients with Somatic Leiomyosarcoma
    Abraham, John A.
    Weaver, Michael J.
    Hornick, Jason L.
    Zurakowski, David
    Ready, John E.
    [J]. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2012, 94A (08) : 736 - 744
  • [2] [Anonymous], 2008, ENZINGER WEISSS SOFT
  • [3] Studying Cancer Treatment in the Elderly Patient Population
    Balducci, Lodovico
    [J]. CANCER CONTROL, 2014, 21 (03) : 215 - 220
  • [4] Efficacy of Adjuvant Radiation Therapy in the Treatment of Soft Tissue Sarcoma of the Extremity: 20-year Follow-Up of a Randomized Prospective Trial
    Beane, Joal D.
    Yang, James C.
    White, Donald
    Steinberg, Seth M.
    Rosenberg, Steven A.
    Rudloff, Udo
    [J]. ANNALS OF SURGICAL ONCOLOGY, 2014, 21 (08) : 2484 - 2489
  • [5] The effect of an unplanned excision of a soft-tissue sarcoma on prognosis
    Chandrasekar, C. R.
    Wafa, H.
    Grimer, R. J.
    Carter, S. R.
    Tillman, R. M.
    Abudu, A.
    [J]. JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2008, 90B (02): : 203 - 208
  • [6] Gastrointestinal Stromal Tumors and Leiomyosarcoma of the Abdomen and Retroperitoneum: A Clinical Comparison
    Bryan M. Clary
    Ronald P. DeMatteo
    Jonathan J. Lewis
    Denis Leung
    Murray F. Brennan
    [J]. Annals of Surgical Oncology, 2001, 8 (4) : 290 - 299
  • [7] Leiomyosarcoma of somatic soft tissues - A tumor of vascular origin with multivariate analysis of outcome in 42 cases
    Farshid, G
    Pradhan, M
    Goldblum, J
    Weiss, SW
    [J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2002, 26 (01) : 14 - 24
  • [8] Fletcher C. D. M. B. J., 2013, WHO Classification of Tumours of Soft Tissue and Bone, V5
  • [9] Predictors of Survival and Recurrence in Primary Leiomyosarcoma
    Gladdy, Rebecca A.
    Qin, Li-Xuan
    Moraco, Nicole
    Agaram, Narasimhan P.
    Brennan, Murray F.
    Singer, Samuel
    [J]. ANNALS OF SURGICAL ONCOLOGY, 2013, 20 (06) : 1851 - 1857
  • [10] Short, Full-Dose Adjuvant Chemotherapy in High-Risk Adult Soft Tissue Sarcomas: A Randomized Clinical Trial From the Italian Sarcoma Group and the Spanish Sarcoma Group
    Gronchi, Alessandro
    Frustaci, Sergio
    Mercuri, Mario
    Martin, Javier
    Lopez-Pousa, Antonio
    Verderio, Paolo
    Mariani, Lidia
    Valagussa, Pinuccia
    Miceli, Rosalba
    Stacchiotti, Silvia
    Dei Tos, Angelo Paolo
    De Paoli, Antonino
    Longhi, Alessandra
    Poveda, Andres
    Quagliuolo, Vittorio
    Comandone, Alessandro
    Casali, Paolo Giovanni
    Picci, Piero
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (08) : 850 - 856
123