GnRH blockers: a changing paradigm in the management of prostate cancer

被引：6
|
作者：
Drudge-Coates, Lawrence [1 ]
机构：
[1] Kings Coll Hosp London, Dept Urol, London SE5 9RS, England
来源：
INTERNATIONAL JOURNAL OF UROLOGICAL NURSING | 2009年 / 3卷 / 03期
关键词：
Androgen deprivation; Degarelix; Gonadotrophin-receptor blocker; Hormonal therapy; Prostate cancer; ANDROGEN DEPRIVATION THERAPY; OPEN-LABEL; HORMONE; CASTRATION; DEGARELIX; TESTOSTERONE; ANTAGONISTS; CARCINOMA; EFFICACY; SAFETY;
D O I：
10.1111/j.1749-771X.2009.01081.x
中图分类号：
R47 [护理学];
学科分类号：
1011 ;
摘要：
The development of GnRH blockers provides a new class of hormonal agent with a different, direct mode of action. Degarelix, a newly approved GnRH blocker, has displayed a fast, profound and sustained suppression of testosterone and prostate-specific antigen levels without subsequent tumour flare effects. This paper considers the current evidence for this new treatment approach and how this may impact on current urology nursing practice.
引用
收藏
页码：85 / 92
页数：8
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