Structural Insights into the Mechanism of Phosphoenolpyruvate Carboxykinase Catalysis

被引:30
作者
Carlson, Gerald M. [1 ]
Holyoak, Todd [1 ]
机构
[1] Univ Kansas, Med Ctr, Dept Biochem & Mol Biol, Kansas City, KS 66160 USA
关键词
CRYSTAL-STRUCTURE; PHOSPHORYL-TRANSFER; PEP-CARBOXYKINASE; STEREOCHEMICAL COURSE; CYTOSOLIC PEPCK; GTP; ANALOGS; INHIBITION; REVEALS; LOOP;
D O I
10.1074/jbc.R109.040568
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:27037 / 27041
页数:5
相关论文
共 50 条
[31]   Crystal structure of the dimeric phosphoenolpyruvate carboxykinase (PEPCK) from Trypanosoma cruzi at 2 A resolution [J].
Trapani, S ;
Linss, J ;
Goldenberg, S ;
Fischer, H ;
Craievich, AF ;
Oliva, G .
JOURNAL OF MOLECULAR BIOLOGY, 2001, 313 (05) :1059-1072
[32]   Inhibition of Pig Phosphoenolpyruvate Carboxykinase Isoenzymes by 3-Mercaptopicolinic Acid and Novel Inhibitors [J].
Hidalgo, Jorge ;
Latorre, Pedro ;
Alberto Carrodeguas, Jose ;
Velazquez-Campoy, Adrian ;
Sancho, Javier ;
Lopez-Buesa, Pascual .
PLOS ONE, 2016, 11 (07)
[33]   Structural insights into the mechanism of archaellar rotational switching [J].
Altegoer, Florian ;
Quax, Tessa E. F. ;
Weiland, Paul ;
Nussbaum, Phillip ;
Giammarinaro, Pietro, I ;
Patro, Megha ;
Li, Zhengqun ;
Oesterhelt, Dieter ;
Grininger, Martin ;
Albers, Sonja-Verena ;
Bange, Gert .
NATURE COMMUNICATIONS, 2022, 13 (01)
[34]   Structural insights into the mechanism of inhibition of AHAS by herbicides [J].
Lonhienne, Thierry ;
Garcia, Mario D. ;
Pierens, Gregory ;
Mobli, Mehdi ;
Nouwens, Amanda ;
Guddat, Luke W. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (09) :E1945-E1954
[35]   Structural Insights into the Mechanism of Phosphoregulation of the Retinoblastoma Protein [J].
Lamber, Ekaterina P. ;
Beuron, Fabienne ;
Morris, Edward P. ;
Svergun, Dmitri I. ;
Mittnacht, Sibylle .
PLOS ONE, 2013, 8 (03)
[36]   A GTP-dependent Phosphoenolpyruvate Carboxykinase from Crassostrea gigas Involved in Immune Recognition [J].
Lv, Zhao ;
Qiu, Limei ;
Wang, Weilin ;
Liu, Zhaoqun ;
Xue, Zhuang ;
Yu, Zichao ;
Song, Xiaorui ;
Chen, Hao ;
Wang, Lingling ;
Song, Linsheng .
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2017, 77 :318-329
[37]   Inhibition of phosphoenolpyruvate carboxykinase blocks lactate utilization and impairs tumor growth in colorectal cancer [J].
Montal, Emily D. ;
Bhalla, Kavita ;
Dewi, Ruby E. ;
Ruiz, Christian F. ;
Haley, John A. ;
Ropell, Ashley E. ;
Gordon, Chris ;
Haley, John D. ;
Girnun, Geoffrey D. .
CANCER & METABOLISM, 2019, 7 (1)
[38]   Structural insights into the catalysis and substrate specificity of cyanobacterial aspartate racemase McyF [J].
Cao, Dong-Dong ;
Zhang, Chun-Peng ;
Zhou, Kang ;
Jiang, Yong-Liang ;
Tan, Xiao-Feng ;
Xie, Jin ;
Ren, Yan-Min ;
Chen, Yuxing ;
Zhou, Cong-Zhao ;
Hou, Wen-Tao .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 514 (04) :1108-1114
[39]   Structural insights into the catalysis and regulation of E3 ubiquitin ligases [J].
Buetow, Lori ;
Huang, Danny T. .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2016, 17 (10) :626-642
[40]   Structural insights into the reaction mechanism of S-adenosyl-L-homocysteine hydrolase [J].
Kusakabe, Yoshio ;
Ishihara, Masaaki ;
Umeda, Tomonobu ;
Kuroda, Daisuke ;
Nakanishi, Masayuki ;
Kitade, Yukio ;
Gouda, Hiroaki ;
Nakamura, Kazuo T. ;
Tanaka, Nobutada .
SCIENTIFIC REPORTS, 2015, 5