Safety Assessment of Sorbitan Esters as Used in Cosmetics

被引：7

作者：

Fiume, Monice M. ^{[1
]}

Bergfeld, Wilma F. ^{[1
]}

Belsito, Donald V. ^{[1
]}

Hill, Ronald A. ^{[1
]}

Klaassen, Curtis D. ^{[1
]}

Liebler, Daniel C. ^{[1
]}

Marks, James G., Jr. ^{[1
]}

Shank, Ronald C. ^{[1
]}

Slaga, Thomas J. ^{[1
]}

Snyder, Paul W. ^{[1
]}

Gill, Lillian J. ^{[1
]}

Heldreth, Bart ^{[1
]}

机构：

[1] Cosmet Ingredient Rev, 1620 L St NW,Suite 1200, Washington, DC 20036 USA

来源：

INTERNATIONAL JOURNAL OF TOXICOLOGY | 2019年 / 38卷

关键词：

safety; cosmetics; sorbitan esters; ALLERGIC CONTACT-DERMATITIS; SESQUIOLEATE; FORMULATION;

D O I：

10.1177/1091581819871877

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The Cosmetic Ingredient Review Expert Panel (Panel) assessed the safety of 20 sorbitan esters; this report included sorbitan esters that were reviewed in 1985 and 2002, as well as 3 previously unreviewed sorbitan esters (sorbitan undecylenate, sorbitan sesquicaprylate, and sorbitan palmate). Most of the sorbitan esters are reported to function in cosmetics as surfactant-emulsifying agents. The Panel reviewed the data from previous sorbitan ester reports, as well as additional data included in this report, to determine the safety of these ingredients. The Panel concluded that the sorbitan esters included in this safety assessment are safe in cosmetics in the present practices of use and concentration.

引用

页码：S60 / S80

页数：21

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