The re-emerging of SADS-CoV infection in pig herds in Southern China

被引：90

作者：

Zhou, Ling ^{[1
,2
]}

Li, Qian N. ^{[1
,2
]}

Su, Jiang N. ^{[1
]}

Chen, Gui H. ^{[1
]}

Wu, Zi X. ^{[1
]}

Luo, Ying ^{[1
]}

Wu, Rui T. ^{[1
,2
]}

Sun, Yuan ^{[1
,2
]}

Lan, Tian ^{[1
]}

Ma, Jing Y. ^{[1
,2
]}

机构：

[1] South China Agr Univ, Coll Anim Sci, Wushan Rd 483, Guangzhou 510642, Guangdong, Peoples R China

[2] Key Lab Anim Hlth Aquaculture & Environm Control, Guangzhou, Guangdong, Peoples R China

来源：

TRANSBOUNDARY AND EMERGING DISEASES | 2019年 / 66卷 / 05期

关键词：

phylogenetic analysis; re-emerging; SADS-CoV; Southern China; SWINE;

D O I：

10.1111/tbed.13270

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A new highly virulent swine acute diarrhoea syndrome coronavirus (SADS-CoV) emerged in Guangdong province in 2017 followed by fatal diarrhoea that involved the death of 24,693 piglets. And yet from May 2017 to January 2019, there were no new SADS cases arising in pig herds in Guangdong. In this study, we reported the recent diarrhoea outbreak of SADS-CoV in Southern China on February 2019. Intestinal samples collected from diarrhoeal piglets were detected for common swine virus and confirmed that SADS-CoV was responsible for the diarrhoea case. Meanwhile, serological investigation of sows' sera implied that SADS-CoV has existed in the farm and PEDV antibody may not directly contribute to the amplification of SADS-CoV. Homology and phylogenetic analysis of the whole genome showed that the re-emerging SADS-CoV strain shared high sequence identities with existing SADS-CoV strains and all strains clustered together in Alpha coronavirus. All in all, the report herein emphasized the re-emerging of SADS-CoV and highlights continuous monitoring for this virus.

引用

页码：2180 / 2183

页数：4

共 12 条

[1] Origin and evolution of pathogenic coronaviruses [J].

Cui, Jie ;

Li, Fang ;

Shi, Zheng-Li .

NATURE REVIEWS MICROBIOLOGY, 2019, 17 (03) :181-192

[2] Porcine Deltacoronavirus in Mainland China [J].

Dong, Nan ;

Fang, Liurong ;

Zeng, Songlin ;

Sun, Qianqian ;

Chen, Huanchun ;

Xiao, Shaobo .

EMERGING INFECTIOUS DISEASES, 2015, 21 (12) :2254-2255

[3]

FELSENSTEIN J, 1985, EVOLUTION, V39, P783, DOI 10.1111/j.1558-5646.1985.tb00420.x

[4] A New Bat-HKU2-like Coronavirus in Swine, China, 2017 [J].

Gong, Lang ;

Li, Jie ;

Zhou, Qingfeng ;

Xu, Zhichao ;

Chen, Li ;

Zhang, Yun ;

Xue, Chunyi ;

Wen, Zhifen ;

Cao, Yongchang .

EMERGING INFECTIOUS DISEASES, 2017, 23 (09) :1607-1609

[5]

Kumar S, 2016, MOL BIOL EVOL, V33, P1870, DOI [10.1093/molbev/msw054, 10.1093/molbev/msv279]

[6]

Li K, 2018, MICROBIOL RESOUR ANN, V7, DOI [10.1128/mra.01259-18, 10.1128/MRA.01259-18]

[7] Cellular entry of the porcine epidemic diarrhea virus [J].

Li, Wentao ;

van Kuppeveld, Frank J. M. ;

He, Qigai ;

Rottier, Peter J. M. ;

Bosch, Berend-Jan .

VIRUS RESEARCH, 2016, 226 :117-127

[8] Discovery of a novel swine enteric alphacoronavirus (SeACoV) in southern China [J].

Pan, Yongfei ;

Tian, Xiaoyan ;

Qin, Pan ;

Wang, Bin ;

Zhao, Pengwei ;

Yang, Yong -Le ;

Wang, Lianxiang ;

Wang, Dongdong ;

Song, Yanhua ;

Zhang, Xiangbin ;

Huang, Yao-Wei .

VETERINARY MICROBIOLOGY, 2017, 211 :15-21

[9] Isolation and characterization of a highly pathogenic strain of Porcine enteric alphacoronavirus causing watery diarrhoea and high mortality in newborn piglets [J].

Xu, Zhichao ;

Zhang, Yun ;

Gong, Lang ;

Huang, Licheng ;

Lin, Ying ;

Qin, Jianru ;

Du, Yunping ;

Zhou, Qingfeng ;

Xue, Chunyi ;

Cao, Yongchang .

TRANSBOUNDARY AND EMERGING DISEASES, 2019, 66 (01) :119-130

[10]

Xuan H., 1984, Chin. J. Vet. Sci, V4, P202

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