The Sleeping Cerebellum

被引：122

作者：

Canto, Cathrin B. ^{[1
]}

Onuki, Yoshiyuki ^{[1
]}

Bruinsma, Bastiaan ^{[1
]}

van der Werf, Ysbrand D. ^{[1
,2
]}

De Zeeuw, Chris I. ^{[1
,3
]}

机构：

[1] Royal Netherlands Acad Arts & Sci, Netherlands Inst Neurosci, NL-1105 BA Amsterdam, Netherlands

[2] Vrije Univ Amsterdam, Med Ctr, Dept Anat & Neurosci, NL-1007 MC Amsterdam, Netherlands

[3] Erasmus MC, Dept Neurosci, NL-3000 DR Rotterdam, Netherlands

来源：

TRENDS IN NEUROSCIENCES | 2017年 / 40卷 / 05期

关键词：

EYE-MOVEMENT SLEEP; CEREBRAL-BLOOD-FLOW; NOREPINEPHRINE-CONTAINING AFFERENTS; MOLECULAR CLOCK COMPONENTS; PURKINJE-CELLS; MEMORY CONSOLIDATION; BRAIN ACTIVITY; CEREBELLOTHALAMIC PATHWAY; CHOLINERGIC INNERVATION; FUNCTIONAL CONNECTIVITY;

D O I：

10.1016/j.tins.2017.03.001

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We sleep almost one-third of our lives and sleep plays an important role in critical brain functions like memory formation and consolidation. The role of sleep in cerebellar processing, however, constitutes an enigma in the field of neuroscience; we know little about cerebellar sleep-physiology, cerebro-cerebellar interactions during sleep, or the contributions of sleep to cerebellum-dependent memory consolidation. Likewise, we do not understand why cerebellar malfunction can lead to changes in the sleep-wake cycle and sleep disorders. In this review, we evaluate how sleep and cerebellar processing may influence one another and highlight which scientific routes and technical approaches could be taken to uncover the mechanisms underlying these interactions.

引用

页码：309 / 323

页数：15

共 155 条

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