How does the multifaceted plant hormone salicylic acid combat disease in plants and are similar mechanisms utilized in humans?

被引：167
作者：
Dempsey, D'Maris Amick [1 ]
Klessig, Daniel F. [1 ]
机构：
[1] Boyce Thompson Inst Plant Res, 533 Tower Rd, Ithaca, NY 14853 USA
来源：
BMC BIOLOGY | 2017年 / 15卷
基金：
美国国家科学基金会;
关键词：
SYSTEMIC ACQUIRED-RESISTANCE; ISOCHORISMATE-SYNTHASE; FLOWERING TIME; TRANSCRIPTION FACTORS; PARTIALLY REDUNDANT; DEFENSE RESPONSES; ARABIDOPSIS EDS1; CELL-DEATH; E3; LIGASE; SIGNAL;
D O I：
10.1186/s12915-017-0364-8
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Salicylic acid (SA) is an important plant hormone that regulates many aspects of plant growth and development, as well as resistance to (a) biotic stress. Efforts to identify SA effector proteins have revealed that SA binds to and alters the activity of multiple plant proteins-this represents a shift from the paradigm that hormones mediate their functions via one or a few receptors. SA and its derivatives also have multiple targets in animals; some of these proteins, like their plant counterparts, are associated with pathological processes. Together, these findings suggest that SA exerts its defense- associated effects in both kingdoms via a large number of targets.
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