(2E,2′E)-2,2′-(1,2,4-Thiadiazole-3,5-diyl)bis[3-arylacrylonitriles]: Synthesis and Antidote Activity Towards 2,4-D Herbicide

被引：2

作者：

Dakhno, P. G. ^{[1
]}

Dotsenko, V. V. ^{[1
,2
]}

Strelkov, V. D. ^{[1
,2
]}

Vasilin, V. K. ^{[3
]}

Aksenov, N. A. ^{[2
]}

Aksenova, I. V. ^{[2
]}

机构：

[1] Kuban State Univ, Krasnodar 350040, Russia

[2] North Caucasus Fed Univ, Stavropol 355009, Russia

[3] Kuban State Technol Univ, Krasnodar 350072, Russia

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2022年 / 92卷 / 12期

关键词：

cyanothioacetamide; 2-cyanothioacrylamides; diethyl sulfoxide; oxidative dimerization of thioamides; 1; 2; 4-thiadiazoles; herbicide antidotes; 3,5-DISUBSTITUTED 1,2,4-THIADIAZOLES; THIOAMIDES; CYANOTHIOACETAMIDE; CHOLINESTERASE; DERIVATIVES; CONVENIENT; INHIBITORS; OXIDATION; BLOCKERS; SYSTEM;

D O I：

10.1134/S1070363222120337

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Oxidation of (E)-3-aryl-2-cyanothioacrylamides under the action of the Et2S(O)-HCl system leads to the formation of (2E,2 ' E)-2,2 '-(1,2,4-thiadiazole-3,5-diyl)bis[3-arylacrylonitriles] in 54-91% yields. Structure of the obtained compounds was confirmed by the two-dimensional NMR spectroscopy data. A plausible reaction mechanism was discussed. Two compounds showed a pronounced antidote effect against 2,4-D herbicide in a laboratory experiment on sunflower seedlings in the absence of growth-stimulating activity.

引用

页码：2822 / 2831

页数：10