Multipotential Capacity of Human Adipose-derived Mesenchymal Stem Cells

被引：0

作者：

Guo, Bao-Feng ^{[1
]}

Zhang, Ling ^{[1
]}

Yin, Wei-Tian ^{[1
]}

Ji, Kun ^{[1
]}

Wei, Zhuang ^{[1
]}

机构：

[1] Jilin Univ, Dept Surg, Prostate Dis Prevent & Treatment Res Ctr, China Japan Union Hosp,Norman Bethune Med Sch, Changchun, Peoples R China

来源：

2010 4TH INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING (ICBBE 2010) | 2010年

基金：

中国国家自然科学基金;

关键词：

articular cartilage; adipose tissue; stem cell; chondrocyte; TISSUE; REGENERATION;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Adipose tissue is derived from the embryonic mesenchyme and can be isolated easily. The purpose of this study was to investigate the multipotent ability of adipose-derived mesenchymal stem cells and to investigate the molecular characterization of adipose-derived mesenchymal stem cells during chondrogenic differentiation in vitro. Our results showed that adipose- derived mesenchymal stem cells have the ability to differentiate into adipogenic, osteogenic, and chondrogenic cells with adipogenic, osteogenic, and chondrogenic medium in vitro. The expression of chondrogenic related molecules were detected by RT-PCR analysis during chondrogenic differentiation. These studies demonstrate that human adipose- derived mesenchymal stem cells have the multipotentiality and adipose tissue may represent a novel approach to form tissue engineering cartilage to heal the damage cartilage.

引用

页数：3

共 50 条

[41] Comparison of bone regenerative capacity of donor-matched human adipose-derived and bone marrow mesenchymal stem cells
Mohamed-Ahmed, Samih
Yassin, Mohammed A.
Rashad, Ahmad
Espedal, Heidi
Idris, Shaza B.
Finne-Wistrand, Anna
Mustafa, Kamal
Vindenes, Hallvard
Fristad, Inge
CELL AND TISSUE RESEARCH, 2021, 383 (03) : 1061 - 1075
[42] Enhanced Osteocyte Differentiation: Cathepsin D and L Secretion by Human Adipose-Derived Mesenchymal Stem Cells
Choi, Jung-Won
Lim, Soyeon
Jung, Seung Eun
Jeong, Seongtae
Moon, Hanbyeol
Song, Byeong-Wook
Kim, Il-Kwon
Lee, Seahyoung
Hwang, Ki-Chul
Kim, Sang Woo
CELLS, 2023, 12 (24)
[43] Human Adipose-Derived Mesenchymal Stem Cells Are Resistant to HBV Infection during Differentiation into Hepatocytes in Vitro
Wang, Ying
Wang, Feng
Zhao, Hongchang
Zhang, Xiaohe
Chen, Haiying
Zhang, Kaiyu
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2014, 15 (04) : 6096 - 6110
[44] Osteogenic Capacity of Human Adipose-Derived Stem Cells is Preserved Following Triggering of Shape Memory Scaffolds
Tseng, Ling-Fang
Wang, Jing
Baker, Richard M.
Wang, Guirong
Mather, Patrick T.
Henderson, James H.
TISSUE ENGINEERING PART A, 2016, 22 (15-16) : 1026 - 1035
[45] Fat Therapeutics: The Clinical Capacity of Adipose-Derived Stem Cells and Exosomes for Human Disease and Tissue Regeneration
Shukla, Lipi
Yuan, Yinan
Shayan, Ramin
Greening, David W.
Karnezis, Tara
FRONTIERS IN PHARMACOLOGY, 2020, 11
[46] Myogenic Differentiation of Human Adipose-Derived Stem Cells
Park, Yoon Ghil
Baek, Ah Mi
Do, Byung Rok
Choi, Jung Hwa
Kim, Sun Do
ANNALS OF REHABILITATION MEDICINE-ARM, 2011, 35 (01): : 8 - 13
[47] The Effect of Age on Human Adipose-Derived Stem Cells
Wu, Wei
Niklason, Laura
Steinbacher, Derek M.
PLASTIC AND RECONSTRUCTIVE SURGERY, 2013, 131 (01) : 27 - 37
[48] Hydrogen peroxide: a potent inducer of differentiation of human adipose-derived stem cells into chondrocytes
Goudarzi, Farjam
Mohammadalipour, Adel
Bahabadi, Majid
Goodarzi, Mohammad Taghi
Sarveazad, Arash
Khodadadi, Iraj I.
FREE RADICAL RESEARCH, 2018, 52 (07) : 763 - 774
[49] Human adipose-derived stem cells: isolation, characterization and applications in surgery
Locke, Michelle
Windsor, John
Dunbar, P. Rod
ANZ JOURNAL OF SURGERY, 2009, 79 (04) : 235 - 244
[50] Manual Isolation of Adipose-derived Stem Cells from Human Lipoaspirates
Zhu, Min
Heydarkhan-Hagvall, Sepideh
Hedrick, Marc
Benhaim, Prosper
Zuk, Patricia
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2013, (79):

← 1 2 3 4 5 →