Antimicrobial Effects of Various Flavonoids on Escherichia coli O157:H7 Cell Growth and Lipopolysaccharide Production

被引：34

作者：

Lee, Kyung-Ah ^{[1
]}

Moon, Sun Hee ^{[1
]}

Kim, Kee-Tae ^{[2
]}

Mendonca, Aubrey F. ^{[3
]}

Paik, Hyun-Dong ^{[1
,2
]}

机构：

[1] Konkuk Univ, Div Anim Life Sci, Seoul 143701, South Korea

[2] Konkuk Univ, Bio Mol Informat Ctr, Seoul 143701, South Korea

[3] Iowa State Univ, Dept Food Sci & Human Nutr, Ames, IA 50011 USA

来源：

FOOD SCIENCE AND BIOTECHNOLOGY | 2010年 / 19卷 / 01期

基金：

新加坡国家研究基金会;

关键词：

flavonoid; Escherichia coli O157:H7; Limulus amebocyte lysate (LAL) assay; antimicrobial effect; lipopolysaccharide; luteolin;

D O I：

10.1007/s10068-010-0037-7

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Flavonoids have biofunctional effects as antioxidant and antimicrobial agents. The objective of this study was to evaluate the bactericidal activity and antilipopolysaccharide (LPS) effects of flavonoids on Escherichia coli O157:H7. The effects of flavonoids on the growth of E coli O157:H7 were bacteriostatic rather than bactericidal at concentrations below 200 mu M, and there was no significant difference among the flavonoids tested (p<0.05). LPS production in E coli O157:H7 treated with 200 mu M quercetin and naringenin decreased by 34.06 +/- 1.03 and 19.90 +/- 1.51%, respectively, relative to the control (no flavonoid). Luteolin, genkwanin, hesperetin, and apigenin caused decreases in LPS production of 69.85 +/- 1.03, 61.18 +/- 1.15, 60.74 +/- 1.10, and 58.93 +/- 0.98%, respectively, relative to the control. Based on these results, luteolin had the greater inhibitory effect on LPS production by E. coli O157:H7 than other flavonoids tested in this study.

引用

页码：257 / 261

页数：5

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