Indel mutations of sheep PLAG1 gene and their associations with growth traits

被引：17
作者：
Pan, Yun [1 ]
Wang, Min [1 ]
Wu, Hui [1 ]
Akhatayeva, Zhanerke [1 ]
Lan, Xianyong [1 ]
Fei, Panfeng [2 ]
Mao, Cui [3 ]
Jiang, Fugui [3 ]
机构：
[1] Northwest A&F Univ, Coll Anim Sci & Technol, Key Lab Anim Genet Breeding & Reprod Shaanxi Prov, Yangling, Shaanxi, Peoples R China
[2] Northwest A&F Univ, Coll Informat Engn, Yangling, Shaanxi, Peoples R China
[3] Shandong Acad Agr Sci, Inst Anim Sci & Vet Med, Shandong Key Lab Anim Dis Control & Breeding, Jinan, Peoples R China
来源：
ANIMAL BIOTECHNOLOGY | 2022年 / 33卷 / 07期
关键词：
Sheep; PLAG1; gene; polymorphism; growth traits; marker-assisted selection (MAS); SELECTION; DELETION; TARGET;
D O I：
10.1080/10495398.2021.1906265
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
Pleiomorphic adenoma gene 1 (PLAG1) is mainly expressed in embryonic development, and it is reported to take an effect on the growth performance of mice, cattle, pigs, and sheep. To explore how conservative the PLAG1 is in different sheep breeds, the effects of the two indel variants on the growth traits of the Chinese Luxi blackhead (LXBH) sheep were firstly detected. The P2-del 30 bp and P4-del 45 bp indel loci of the sheep PLAG1 gene were significantly related to 15 growth traits (P < 0.05). Genotype ID and genotype II were dominant for the P2-del 30 bp and P4-del 45 bp loci, respectively. The above findings indicated that the two indel mutations in the ovine PLAG1 gene were suggested to become the molecular markers for the selection of economic traits in sheep.
引用
收藏
页码：1459 / 1465
页数：7
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