共 35 条
The ubiquitin proteasome system and its involvement in cell death pathways
被引:32
作者:

Bernassola, F.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Roma Tor Vergata, Dept Expt Med & Biochem Sci, Biochem Lab, IDI IRCCS, Rome, Italy Univ Roma Tor Vergata, Dept Expt Med & Biochem Sci, Biochem Lab, IDI IRCCS, Rome, Italy

Ciechanover, A.
论文数: 0 引用数: 0
h-index: 0
机构:
Technion Israel Inst Technol, Rappaport Fac Med, Canc & Vasc Biol Res Ctr, IL-31906 Haifa, Israel
Technion Israel Inst Technol, Res Inst, IL-31906 Haifa, Israel Univ Roma Tor Vergata, Dept Expt Med & Biochem Sci, Biochem Lab, IDI IRCCS, Rome, Italy

Melino, G.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Roma Tor Vergata, Dept Expt Med & Biochem Sci, Biochem Lab, IDI IRCCS, Rome, Italy
MRC, Toxicol Unit, Leicester, Leics, England Univ Roma Tor Vergata, Dept Expt Med & Biochem Sci, Biochem Lab, IDI IRCCS, Rome, Italy
机构:
[1] Univ Roma Tor Vergata, Dept Expt Med & Biochem Sci, Biochem Lab, IDI IRCCS, Rome, Italy
[2] Technion Israel Inst Technol, Rappaport Fac Med, Canc & Vasc Biol Res Ctr, IL-31906 Haifa, Israel
[3] Technion Israel Inst Technol, Res Inst, IL-31906 Haifa, Israel
[4] MRC, Toxicol Unit, Leicester, Leics, England
基金:
英国医学研究理事会;
关键词:
PROTEIN-DEGRADATION;
IN-VIVO;
INHIBITOR;
APOPTOSIS;
CANCER;
P53;
ACTIVATION;
BORTEZOMIB;
LYSOSOME;
COMPLEX;
D O I:
10.1038/cdd.2009.189
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
[No abstract available]
引用
收藏
页码:1 / 3
页数:3
相关论文
共 35 条
- [1] Development of the proteasome inhihitor Veleade™ (Bortezomib)[J]. CANCER INVESTIGATION, 2004, 22 (02) : 304 - 311Adams, J论文数: 0 引用数: 0 h-index: 0机构: Millennium Pharmaceut Inc, Cambridge, MA USA Millennium Pharmaceut Inc, Cambridge, MA USAKauffman, M论文数: 0 引用数: 0 h-index: 0机构: Millennium Pharmaceut Inc, Cambridge, MA USA Millennium Pharmaceut Inc, Cambridge, MA USA
- [2] Dissecting the role of ubiquitylation in the DNA damage response checkpoint in G2[J]. CELL DEATH AND DIFFERENTIATION, 2010, 17 (01) : 78 - 85Bassermann, F.论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Munich, Dept Med 3, D-81675 Munich, Germany Tech Univ Munich, Dept Med 3, D-81675 Munich, GermanyPagano, M.论文数: 0 引用数: 0 h-index: 0机构: NYU, Sch Med, Smilow Res Ctr, NYU Canc Inst,Dept Pathol, New York, NY 10016 USA Howard Hughes Med Inst, Chevy Chase, MD USA Tech Univ Munich, Dept Med 3, D-81675 Munich, Germany
- [3] The role of ubiquitylation for the control of cell death in Drosophila[J]. CELL DEATH AND DIFFERENTIATION, 2010, 17 (01) : 61 - 67Bergmann, A.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Dept Biochem & Mol Biol, Grad Program Genes & Dev, Houston, TX 77030 USA Univ Texas MD Anderson Canc Ctr, Dept Biochem & Mol Biol, Grad Program Genes & Dev, Houston, TX 77030 USA
- [4] The HECT family of E3 ubiquitin ligases: Multiple players in cancer development[J]. CANCER CELL, 2008, 14 (01) : 10 - 21Bernassola, Francesca论文数: 0 引用数: 0 h-index: 0机构: Univ Roma Tor Vergata, Dept Expt Med & Biochem Sci, Biochem IDI IRCCS Lab, I-00133 Rome, Italy Univ Calif San Diego, Sch Med, Lab Gene Regulat & Signal Transduct, La Jolla, CA 92093 USAKarin, Michael论文数: 0 引用数: 0 h-index: 0机构: Univ Calif San Diego, Sch Med, Lab Gene Regulat & Signal Transduct, La Jolla, CA 92093 USA Univ Calif San Diego, Sch Med, Lab Gene Regulat & Signal Transduct, La Jolla, CA 92093 USACiechanover, Aaron论文数: 0 引用数: 0 h-index: 0机构: Technion Israel Inst Technol, Rappaport Fac Med, Canc & Vasc Biol Ctr, IL-31096 Haifa, Israel Technion Israel Inst Technol, Res Inst, IL-31096 Haifa, Israel Univ Calif San Diego, Sch Med, Lab Gene Regulat & Signal Transduct, La Jolla, CA 92093 USAMelino, Gerry论文数: 0 引用数: 0 h-index: 0机构: Univ Leicester, MRC, Toxicol Unit, Leicester LE1 9HN, Leics, England Univ Roma Tor Vergata, Dept Expt Med & Biochem Sci, Biochem IDI IRCCS Lab, I-00133 Rome, Italy Univ Calif San Diego, Sch Med, Lab Gene Regulat & Signal Transduct, La Jolla, CA 92093 USA
- [5] Identification of the familial cylindromatosis tumour-suppressor gene[J]. NATURE GENETICS, 2000, 25 (02) : 160 - 165Bignell, GR论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandWarren, W论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandSeal, S论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandTakahashi, M论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandRapley, E论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandBarfoot, R论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandGreen, H论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandBrown, C论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandBiggs, PJ论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandLakhani, SR论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandJones, C论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandHansen, J论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandBlair, E论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandHofmann, B论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandSiebert, R论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandTurner, G论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandEvans, DG论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandSchrander-Stumpel, C论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandBeemer, FA论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, Englandvan den Ouweland, A论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandHalley, D论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandDelpech, B论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandCleveland, MG论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandLeigh, I论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandLeisti, J论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandRasmussen, S论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandWallace, MR论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandFenske, C论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandBanerjee, P论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandOiso, N论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandChaggar, R论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandMerrett, S论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandLeonard, N论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandHuber, M论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandHohl, D论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandChapman, P论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandBurn, J论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandSwift, S论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandSmith, A论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandAshworth, A论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, EnglandStratton, MR论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Sect Canc Genet, Sutton, Surrey, England Inst Canc Res, Sect Canc Genet, Sutton, Surrey, England
- [6] A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib[J]. CANCER CELL, 2005, 8 (05) : 407 - 419Chauhan, D论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USACatley, L论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USALi, GL论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USAPodar, K论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USAHideshima, T论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USAVelankar, M论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USAMitsiades, C论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USA论文数: 引用数: h-index:机构:Yasui, H论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USALetai, A论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USAOvaa, H论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USABerkers, C论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USANicholson, B论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USAChao, TH论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USANeuteboom, STC论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USARichardson, P论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USAPalladino, MA论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USAAnderson, KC论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med Oncol,Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USA
- [7] Proteolysis: from the lysosome to ubiquitin and the proteasome[J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2005, 6 (01) : 79 - 86Ciechanover, A论文数: 0 引用数: 0 h-index: 0机构: Technion Israel Inst Technol, Canc & Vasc Biol Res Ctr, Rappaport Fac Med, IL-31096 Haifa, Israel
- [8] Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting[J]. CELL DEATH AND DIFFERENTIATION, 2005, 12 (09) : 1178 - 1190Ciechanover, A论文数: 0 引用数: 0 h-index: 0机构: Technion Israel Inst Technol, Rappaport Fac Med & Res Inst, Canc & Vasc Biol Res Ctr, IL-31096 Haifa, Israel Technion Israel Inst Technol, Rappaport Fac Med & Res Inst, Canc & Vasc Biol Res Ctr, IL-31096 Haifa, Israel
- [9] Therapeutic strategies within the ubiquitin proteasome system[J]. CELL DEATH AND DIFFERENTIATION, 2010, 17 (01) : 4 - 13Eldridge, A. G.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Cell Regulat, San Francisco, CA 94080 USA Genentech Inc, Dept Cell Regulat, San Francisco, CA 94080 USAO'Brien, T.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Cell Regulat, San Francisco, CA 94080 USA Genentech Inc, Dept Cell Regulat, San Francisco, CA 94080 USA
- [10] XIAP as a ubiquitin ligase in cellular signaling[J]. CELL DEATH AND DIFFERENTIATION, 2010, 17 (01) : 54 - 60Galban, S.论文数: 0 引用数: 0 h-index: 0机构: Univ Michigan, Sch Med, Dept Pathol, Ann Arbor, MI 48109 USA Univ Michigan, Sch Med, Dept Pathol, Ann Arbor, MI 48109 USADuckett, C. S.论文数: 0 引用数: 0 h-index: 0机构: Univ Michigan, Sch Med, Dept Pathol, Ann Arbor, MI 48109 USA Univ Michigan, Sch Med, Dept Internal Med, Ann Arbor, MI 48109 USA Univ Michigan, Sch Med, Dept Pathol, Ann Arbor, MI 48109 USA