New fluorescent zinc complexes: towards specific sensors for hydrogen sulfide in solution

被引：64
作者：
Galardon, Erwan [1 ]
Tomas, Alain [2 ,3 ]
Roussel, Pascal [4 ]
Artaud, Isabelle [1 ]
机构：
[1] Univ Paris 05, CNRS, UMR 8601, Lab Chim & Biochim Toxicol & Pharmacol, F-75270 Paris 06, France
[2] Univ Paris 05, CNRS, UMR 8015, RMN Biol, F-75270 Paris 06, France
[3] Univ Paris 05, Lab Cristallog, F-75270 Paris 06, France
[4] ENSCL, CNRS, UMR 8012, UCCS, F-59652 Villeneuve Dascq, France
来源：
DALTON TRANSACTIONS | 2009年 / 42期
关键词：
AQUEOUS-SOLUTION; GASEOUS TRANSMITTER; CHEMISTRY; ANALOGS; REACTIVITY; LIGANDS; ENZYMES; GAS; AIR; H2S;
D O I：
10.1039/b907115f
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Two new fluorescent zinc complexes 1 and 2 have been synthesized by reaction of the complex Tp(Ph,Me)Zn(OH) with 7-hydroxy-4-methylcoumarin (MUH) or 7-mercapto-4-methylcoumarin (MUSH). While the alcoholato derivative TpPh, MeZn(MU) 1 is not efficient for sensing hydrogen sulfide, the thiolato complex Tp(Ph,Me)Zn(MUS) 2 is a colorimetric "turn-on" and fluorescence "turn-off" sensor which shows high selectivity for hydrogen sulfide in the presence of additional thiols like cysteine or glutathione.
引用
收藏
页码：9126 / 9130
页数：5
相关论文
共 49 条
[21]   Electrochemical detection of sulphide: a novel dual flow cell [J].
Lawrence, NS ;
Davis, J ;
Marken, F ;
Jiang, L ;
Jones, TGJ ;
Davies, SN ;
Compton, RG .
SENSORS AND ACTUATORS B-CHEMICAL, 2000, 69 (1-2) :189-192
[22]   Analytical strategies for the detection of sulfide: a review [J].
Lawrence, NS ;
Davis, J ;
Compton, RG .
TALANTA, 2000, 52 (05) :771-784
[23]   Putative biological roles of hydrogen sulfide in health and disease: a breath of not so fresh air? [J].
Li, L. ;
Moore, P. K. .
TRENDS IN PHARMACOLOGICAL SCIENCES, 2008, 29 (02) :84-90
[24]   MONOMERIC ALKYL AND HYDRIDE DERIVATIVES OF ZINC SUPPORTED BY POLY(PYRAZOLYL)HYDROBORATO LIGATION - SYNTHETIC, STRUCTURAL, AND REACTIVITY STUDIES [J].
LOONEY, A ;
HAN, R ;
GORRELL, IB ;
CORNEBISE, M ;
YOON, K ;
PARKIN, G ;
RHEINGOLD, AL .
ORGANOMETALLICS, 1995, 14 (01) :274-288
[25]  
Lowicka E, 2007, PHARMACOL REP, V59, P4
[26]   2ND DISSOCIATION-CONSTANT OF HYDROGEN-SULFIDE [J].
MEYER, B ;
WARD, K ;
KOSHLAP, K ;
PETER, L .
INORGANIC CHEMISTRY, 1983, 22 (16) :2345-2346
[27]   A fluorescent anion sensor that works in neutral aqueous solution for bioanalytical application [J].
Mizukami, S ;
Nagano, T ;
Urano, Y ;
Odani, A ;
Kikuchi, K .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (15) :3920-3925
[28]   Turn-on fluorescence sensing of nucleoside polyphosphates using a xanthene-based Zn(II) complex chemosensor [J].
Ojida, Akio ;
Takashima, Ippei ;
Kohira, Takahiro ;
Nonaka, Hiroshi ;
Hamachi, Itaru .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (36) :12095-12101
[29]   Synthetic analogues relevant to the structure and function of zinc enzymes [J].
Parkin, G .
CHEMICAL REVIEWS, 2004, 104 (02) :699-767
[30]  
Patnaik P.A., 1999, Comprehensive Guide to the Hazardous Properties of Chemical Substances, V2nd
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