MEDI 75-Synthesis of analogs of trienomycin A, a potential inhibitor of Hsp90

被引：0
|
作者：
Calvet, Geraldine [1 ]
Blagg, Brian [1 ]
机构：
[1] Univ Kansas, Dept Med Chem, Lawrence, KS 66045 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 235卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
75-MEDI
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Gambogic Acid, a Natural Product Inhibitor of Hsp90
    Davenport, Jason
    Manjarrez, Jacob R.
    Peterson, Laura
    Krumm, Brian
    Blagg, Brian S. J.
    Matts, Robert L.
    JOURNAL OF NATURAL PRODUCTS, 2011, 74 (05): : 1085 - 1092
  • [42] Identification and initial SAR of silybin: An Hsp90 inhibitor
    Zhao, Huiping
    Brandt, Gary E.
    Galam, Lakshmi
    Matts, Robert L.
    Blagg, Brian S. J.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (09) : 2659 - 2664
  • [43] Identification of vibsanin A analog as a novel HSP90 inhibitor
    Miura, Kazuki
    Matsuki, Wataru
    Ogura, Akihiro
    Takao, Ken-ichi
    Simizu, Siro
    BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 28 (02)
  • [44] A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells
    Zhang, Tao
    Hamza, Adel
    Cao, Xianhua
    Wang, Bing
    Yu, Shuwen
    Zhan, Chang-Guo
    Sun, Duxin
    MOLECULAR CANCER THERAPEUTICS, 2008, 7 (01) : 162 - 170
  • [45] Structures of Hsp90α and Hsp90β bound to a purine-scaffold inhibitor reveal an exploitable residue for drug selectivity
    Huck, John D.
    Que, Nanette L. S.
    Sharma, Sahil
    Taldone, Tony
    Chiosis, Gabriela
    Gewirth, Daniel T.
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2019, 87 (10) : 869 - 877
  • [46] Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor
    Li, Ting
    Chen, Xin
    Dai, Xiao-Yang
    Wei, Bin
    Weng, Qin-Jie
    Chen, Xiuping
    Ouyang, De-Fang
    Yan, Ru
    Huang, Zhang-Jian
    Jiang, Hu-Lin
    Zhu, Hong
    Lu, Jin-Jian
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017, 330 : 65 - 73
  • [47] MEDI 135-Hsp90 inhibitors: Studies towards the geldanamycin analogs
    Blagg, Brian
    Chaudhury, Subhabrata
    Peng, Weimin
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232
  • [48] Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor
    Barluenga, Sofia
    Wang, Cuihua
    Fontaine, Jean-Gonzague
    Aouadi, Kaiss
    Beebe, Kristin
    Tsutsumi, Shinji
    Neckers, Len
    Winssinger, Nicolas
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (23) : 4432 - 4435
  • [49] The design and synthesis of a novel orally available Hsp90 inhibitor CH5164840
    Suda, A.
    Koyano, H.
    Kawasaki, K.
    Ono, N.
    Shiratori, Y.
    Hasegawa, K.
    Fukami, T.
    Miura, T.
    Saito, R.
    Shimma, N.
    Tsukuda, T.
    EJC SUPPLEMENTS, 2010, 8 (07): : 37 - 37
  • [50] Analysis of expression of heat shock protein-90 (HSP90) and the effects of HSP90 inhibitor (17-AAG) in multiple myeloma
    Duus, J.
    Bahar, H. I.
    Venkataraman, G.
    Ozpuyan, F.
    Izban, K. F.
    Al-Masri, H.
    Maududi, T.
    Toor, A.
    Alkan, S.
    LEUKEMIA & LYMPHOMA, 2006, 47 (07) : 1369 - 1378
12345