Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner

被引:3
作者
Itoh, Tadashi [1 ]
Kawabe, Mifumi [2 ]
Nagase, Takahiko [1 ]
Endo, Katsumi [1 ]
Miyoshi, Masafumi [3 ]
Miyahara, Kazuro [3 ]
机构
[1] Nihon Biores Inc, 6-104 Majima,Fukujucho, Gifu 5016251, Japan
[2] Gifu Univ, Fac Appl Biol Sci, Anim Med Ctr, 1-1 Yanagido, Gifu 5011193, Japan
[3] Obihiro Univ Agr & Vet Med, Vet Med Ctr, Inadacho, Obihiro, Hokkaido 0808555, Japan
关键词
body surface area; computed tomography (CT); CT scanner; guinea pig; Hartley;
D O I
10.1292/jvms.20-0525
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The body surface area (BSA) of animals is generally estimated by multiplying the k value (constant) by the measured body weight (BW) raised to the power of 2/3 (Meeh's formula). Computed tomography (CT) scanners generate detailed 3-dimensional (3D) images of objects, and image analysis does not depend on operator skill. Therefore, the analysis of CT images provides accurate and reproducible BSA measurements. In this study, we measured the BSA of 25 male Hartley guinea pigs from 3 to 36 weeks of age (working BW range: 0.233 to 1.160 kg) using a CT scanner and 3D analysis software. We concluded that the k value for male Hartley guinea pigs was 8.37, based on the mean k value of the 25 animals.
引用
收藏
页码:142 / 145
页数:4
相关论文
共 19 条
  • [1] Charles R, 1982, USDA TECHNICAL B, V1, P1
  • [2] Clemons D. J., 2011, LAB GUINEA PIG, P1
  • [3] Draize JH, 1959, APPRAISAL SAFETY CHE, P46
  • [4] Food and Drug Administration, 2005, GUID IND EST MAX SAF
  • [5] Fougere B.J., 2007, Veterinary Herbal Medicine, P221, DOI [10.1016/B978-0-323-02998-8.50018-4, DOI 10.1016/B978-0-323-02998-8.50018-4]
  • [6] HONG CC, 1977, LAB ANIM SCI, V27, P474
  • [7] International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use, 2013, ICH HARM TRIP GUID S
  • [8] Measurements of body surface area and volume in male Japanese White rabbits using a computed tomography scanner: comparison with male New Zealand White rabbits
    Itoh, Tadashi
    Kawabe, Mifumi
    Nagase, Takahiko
    Endo, Katsumi
    Miyoshi, Masafumi
    Miyahara, Kazuro
    [J]. EXPERIMENTAL ANIMALS, 2019, 68 (04) : 429 - 434
  • [9] Measurements of body surface area and volume in laboratory rabbits (New Zealand White rabbits) using a computed tomography scanner
    Itoh, Tadashi
    Kawabe, Mifumi
    Nagase, Takahiko
    Koike, Tsuneo
    Miyoshi, Masafumi
    Miyahara, Kazuro
    [J]. EXPERIMENTAL ANIMALS, 2018, 67 (04) : 527 - 534
  • [10] Body surface area measurement in juvenile miniature pigs using a computed tomography scanner
    Itoh, Tadashi
    Kawabe, Mifumi
    Nagase, Takahiko
    Matsushita, Hisami
    Kato, Masami
    Miyoshi, Masafumi
    Miyahara, Kazuro
    [J]. EXPERIMENTAL ANIMALS, 2017, 66 (03) : 229 - 233