NEURON-GLIA INTERACTIONS Astroglial networks: a step further in neuroglial and gliovascular interactions

被引：564

作者：

Giaume, Christian ^{[1
]}

Koulakoff, Annette ^{[1
]}

Roux, Lisa ^{[1
]}

Holcman, David ^{[2
]}

Rouach, Nathalie ^{[1
]}

机构：

[1] Coll France, INSERM, U840, F-75005 Paris, France

[2] Ecole Normale Super, Dept Biol & Math, F-75005 Paris, France

来源：

NATURE REVIEWS NEUROSCIENCE | 2010年 / 11卷 / 02期

关键词：

ASTROCYTIC GAP-JUNCTIONS; CULTURED ASTROCYTES; SPINAL-CORD; SYNAPTIC-TRANSMISSION; ELECTROPHYSIOLOGICAL PROPERTIES; HIPPOCAMPAL ASTROCYTES; CONNEXIN43; EXPRESSION; EPILEPTIFORM ACTIVITY; POSTNATAL-DEVELOPMENT; GLUCOSE-UTILIZATION;

D O I：

10.1038/nrn2757

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Dynamic aspects of interactions between astrocytes, neurons and the vasculature have recently been in the neuroscience spotlight. It has emerged that not only neurons but also astrocytes are organized into networks. Whereas neuronal networks exchange information through electrical and chemical synapses, astrocytes are interconnected through gap junction channels that are regulated by extra- and intracellular signals and allow exchange of information. This intercellular communication between glia has implications for neuroglial and gliovascular interactions and hence has added another level of complexity to our understanding of brain function.

引用

页码：87 / 99

页数：13

共 151 条

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